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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39703 | ATRA-biotin | ATRA-biotin,Biotin-ATRA-conjugate | |
ATRA-biotin is a biotin-conjugated form of all-trans retinoic acid (ATRA). It is utilized for the purpose of tracking ATRA within cells or specific tissues. | |||
T35629 | ATRA-BA Hybrid | ||
ATRA-BA hybrid is a mutual prodrug form of all-transretinoic acid and butyric acid .1ATRA-BA hybrid is cleaved to release ATRA and BA in isolated mouse plasma. It inhibits the growth of MDA-MB-231 breast and PC3 prostate... | |||
T17733 | ATRA-hydroxyimino | CRABP-II ligand 1 | Others |
ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation o... | |||
T1051 | Retinoic acid | Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin | Retinoid Receptor , Endogenous Metabolite , PPAR , Autophagy |
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferat... | |||
T67921 | Retinoic acid-d5 | all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5 | Retinoid Receptor |
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a meta... | |||
T23154 | Piclamilast | RPR 73401,RP 73401 | PDE |
Piclamilast (RP 73401) is a PDE4 inhibitor. | |||
T5626 | Atrazine | Aktikon,Chromozin,Gesaprim,Oleogesaprim | Others |
Atrazine (Oleogesaprim) is an herbicide that does not occur naturally,and is a selective triazine herbicide. Atrazine (Oleogesaprim) is also a potent endocrine disruptor. | |||
T5642 | Tegatrabetan | BC2059 | Wnt/beta-catenin |
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity. | |||
T5657 | Veratraldehyde | 3,4-Dimethoxybenzaldehyde | Antifungal |
Veratraldehyde (3,4-Dimethoxybenzaldehyde) has antifungal activity .It is found in Cymbopogon javanensis. | |||
TQ0270 | Atrasentan hydrochloride | (+)-A 127722 hydrochloride,ABT-627 hydrochloride,A-147627 hydrochloride | Endothelin Receptor |
Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA). | |||
T7221 | Satraplatin | BMS182751,JM216,BMY45594 | DNA Alkylator/Crosslinker , DNA Alkylation |
Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies. | |||
T11994 | Melagatran | Thrombin | |
Melagatran, a direct and orally active thrombin inhibitor, specifically inhibits thrombin without affecting other enzymes in the coagulation cascade or fibrinolytic enzymes. It does not rely on endogenous co-factors to e... | |||
T12015 | Methyl homoveratrate | Others | |
Methyl homoveratrate, a McN5691 (RWJ-26240) metabolite detected in vivo in plasma, urine, and fecal extracts, functions as a voltage-sensitive calcium channel blocker. | |||
TN3340 | Acetylatractylodinol | Tractylodinol acetate | Others |
Acetylatractylodinol (Tractylodinol acetate) is a natural product isolated from Atractylodes lancea, possesses antioxidant activity. | |||
T1459 | Cisatracurium besylate | 51W89 | Adrenergic Receptor , AChR , Autophagy |
Cisatracurium besylate (51W89) is a nondepolarizing skeletal muscle relaxant for intravenous administration. | |||
T30191L | Atecegatran TFA | Atecegatran TFA(917904-13-3 Free base),AR-H067637 TFA | Others |
Atecegatran TFA is often used as an anticoagulant and can be used to treat cardiovascular disease. | |||
T31806 | Flovagatran | TGN 255 | Thrombin |
Flovagatran (TGN 255) is an orally active, potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism. | |||
TQ0259 | Atrasentan | A-147627,(+)-A 127722,ABT-627 | Endothelin Receptor |
Atrasentan (ABT-627) (ABT-627) is an endothelin receptor antagonist (IC50: 0.0551 nM for ETA). | |||
T17265 | Ximelagatran | EXANTA,H 376-95,H37695,H 376/95,H-37695,H 37695 | Thrombin |
Ximelagatran (H 376-95), a direct thrombin inhibitor, can be taken orally and acts solely by inhibiting the actions of thrombin. Ximelagatran is converted to the active agent melagatran in vivo. | |||
T16098 | Islatravir | MK-8591 | HIV Protease , Reverse Transcriptase |
Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively). |