aldh — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4778	3-Hydroxybenzaldehyde		Others , Dehydrogenase
	3-Hydroxybenzaldehyde is a compound useful in organic synthesis.		Others , Dehydrogenase
TJS1382	Taraxerone		Dehydrogenase
	Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dep...		Dehydrogenase
T12196	NCT-505		Dehydrogenase
	NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57 μM, 22.8 μM, 20.1 μM, >57 μM respectively...		Dehydrogenase
T6903	NCT-501	NCT501	Dehydrogenase
	NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.		Dehydrogenase
T2662	Alda-1	Alda 1	Apoptosis , Dehydrogenase
	Alda-1 is an ALDH2 agonist, a cell-permeable activator of both the wild-type ALDH21 and the Asian E487K mutant ALDH22 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).		Apoptosis , Dehydrogenase
T4S0878	Prunetin	Prunusetin	ERK , Dehydrogenase , NF-κB
	1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...		ERK , Dehydrogenase , NF-κB
T10140	4-Diethylaminobenzaldehyde		Dehydrogenase
	4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1). It displays a potent anti-androgenic effect (IC50: 1.71μM).		Dehydrogenase
T23533	WIN 18446		Dehydrogenase
	inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)		Dehydrogenase
T7835	CM10	CM 10	Dehydrogenase
	CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.		Dehydrogenase
T10148	4-Hydroxynonenal	4-HNE	Dehydrogenase , Endogenous Metabolite
	4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).		Dehydrogenase , Endogenous Metabolite
T0054	Disulfiram	Tetraethylthiuram disulfide,NSC 190940,TETD	Dehydrogenase , Interleukin , Pyroptosis
	Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutely sensitized to alcohol and also inhibits GSDMD pore format...		Dehydrogenase , Interleukin , Pyroptosis
T1389	Dyclonine hydrochloride	Dyclocaine hydrochloride,Dyclonine HCl	Sodium Channel , Antibacterial , Antifungal
	Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .		Sodium Channel , Antibacterial , Antifungal
T15022	CVT-10216		Dehydrogenase
	CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50: 29 nM). CVT-10216 also has inhibitory effect of ALDH-1 (IC50: 1.3 μM). CVT-10216 can reduce excessive alcohol drinking...		Dehydrogenase
T39675	ALDH1A2-IN-1	ALDH1A2-IN-1
	ALDH1A2-IN-1 is a reversible inhibitor of the active site of ALDH1A2, showing a significant affinity for the enzyme with an IC50 value of 0.91 μM and a Kd value of 0.26 μM. This compound interacts hydrophobically with th...
T60240	ALDH1A3-IN-2		Dehydrogenase
	ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.		Dehydrogenase
T67832	ALDH2 modulator 1		Dehydrogenase
	ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.		Dehydrogenase
T63341	ALDH1A1-IN-2		Dehydrogenase
	ALDH1A1-IN-2 is a potent aldehyde dehydrogenase 1a1 (aldh1a1) inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity.		Dehydrogenase
T60372	ALDH3A1-IN-1
	ALDH3A1-IN-1 (Compound 18) is a potent ALDH3A1 inhibitor with an IC 50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination...
T64347	ALDH1A3-IN-3		Dehydrogenase
	ALDH1A3-IN-3 (compound 16), a powerful ALDH1A3 inhibitor with an IC50 of 0.26 μM, serves as an effective ALDH3A1 substrate. It is utilized in prostate cancer research.		Dehydrogenase
T60275	ALDH3A1-IN-2
	ALDH3A1-IN-2 (Compound 19), a potent inhibitor of aldehyde dehydrogenases (ALDHs), demonstrates high efficacy against ALDH3A1 with an IC50 of 1.29 μM. Given the overexpression of ALDHs in multiple tumor types, including ...