ach — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9193	ACH-000143		Melatonin Receptor , MT Receptor
	ACH-000143 have been identified as a novel agonist of the melatonin receptors MT1 and MT2.		Melatonin Receptor , MT Receptor
T28830	Sovaprevir	ACH 0141625,ACH0141625,ACH-0141625,ACH1625,ACH 1625,ACH-1625	HCV Protease
	Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.		HCV Protease
T8509	Danicopan	ACH-4471	Complement System
	Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the ...		Complement System
T14095	ACH-806	GS9132	HCV Protease
	ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.		HCV Protease
T23613	ACH-702
	ACH-702 is an agent of anti-tubercular. ACH-702 is an effective, bactericidal compound with activity against many antibiotic-resistant pathogens.
T1221	Acetylcholine chloride	ACh chloride,Pilofrin	Calcium Channel , Endogenous Metabolite , AChR
	Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pilofrin) mimics the parasympathomimetic effect of the endogen...		Calcium Channel , Endogenous Metabolite , AChR
T39493	Vemircopan	ACH0145228,ACH-5228,ALXN2050
	Vemircopan is a complement factor D inhibitor.
T27256	Elvucitabine	ACH126443,TY-202,L-D-4FC,beta-L-Fd-4C,ACH 126443,ACH-126443
	Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.
T6751	Acetylcholine iodide	Acetylcolina	Others
	Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the cent...		Others
T70729	Indisetron
	Indisetron is a 5-HT(3) and 5-HT(4) receptor antagonist. Indisetron reduces 2-methyl-5-serotonin (HT)-induced bradycardia.
T28069	ML380	ML 380,ML-380	AChR
	ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).		AChR
T2227	Hemicholinium 3	Hemicholinium-3,Hemicholine	Others , AChE
	Hemicholinium 3 is a potent and selective choline uptake blocker.		Others , AChE
T71029	RCC-36 HCl
	Rcc 36 is an active metabolite of temiverine that has inhibitory actions toward the atropine-resistant part of contractions, which may be related to the calcium antagonistic actions of these compounds.
TN1653	Fustin		ERK , Beta Amyloid , AChR
	Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.		ERK , Beta Amyloid , AChR
T9889	M4 mAChR agonist-1	4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-	AChR
	M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).		AChR
T61969	AChE/BChE-IN-10		AChR , AChE
	AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation...		AChR , AChE
T22021	ACHP	IKK-2 Inhibitor VIII	IκB/IKK
	ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression thro...		IκB/IKK
TN7250	Torachrysone Triglucoside	1-[8-[(O-β-D-Glucopyranosyl-(1→3)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl)oxy]-1-hydroxy-6-methoxy-3-methyl-2-naphthalenyl]ethanone	Others
	Torachrysone Triglucoside is a glucoside isolated from cassia seeds with potential antitumor activity.		Others
T9417L	Gamma-preprotachykinin amide (72-92) acetate	gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)	Others
	gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate po...		Others
TN7253	Torachrysone gentiobioside
	Torachrysone gentiobioside is a phenolic glycoside isolated from cassia seeds.