a-118 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T28883	Sultroponium	A118,A-118,A 118
	Sultroponium may be used as an anticholinergic agent or antispasmodic.
T6735	XL413 hydrochloride	BMS-863233 Hydrochloride,XL413,BMS-863233	cholecystokinin , Casein Kinase , Pim , CDK
	XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC 50 of 3.4 nM. XL413 hydrochloride also exhibits potent effect with IC 50 s of 215, 42 nM on CK2, PIM...		cholecystokinin , Casein Kinase , Pim , CDK
T3355	Naloxegol oxalate	NKTR-118,NKTR-118 oxalate,AZ 13337019,AZ-13337019 oxalate	P450
	Naloxegol oxalate (NKTR-118) is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation.		P450
T6100	Torin 2		Apoptosis , ATM/ATR , DNA-PK , mTOR , Autophagy
	Torin 2(IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold greater specific activity for mTOR than PI3K and improves pharmacokinetic properties. The EC50 of Torin 2 for ATM/ATR/DNA-PK inhibition is 2...		Apoptosis , ATM/ATR , DNA-PK , mTOR , Autophagy
T36374	Naloxegol (NKTR-118)
	Naloxegol (NKTR-118; AZ-13337019) is an opioid-receptor antagonist[1]. [1]. Yoon SC, et al. Naloxegol in opioid-induced constipation: a new paradigm in the treatment of a common problem. Patient Prefer Adherence. 2017 Ju...
TP1077	Nucleoprotein (118-126)	Nucleoprotein 118-126,NP(118-126)
	Nucleoprotein (118-126),a fragment of Nucleoprotein, is a 9-aa peptide .
T38050	CP-609754		Transferase
	CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n...		Transferase
T75887	[Ala113]MBP(104-118) TFA
	[Ala113]MBP(104-118) TFA is a peptide inhibitor operating noncompetitively against protein kinase C (PKC), exhibiting inhibitory concentrations (IC50) in the range of 28-62 μM [1].
T65704	2-(Hydroxymethyl)isoindoline-1,3-dione
	2-(Hydroxymethyl)isoindoline-1,3-dione is a useful organic compound for research related to life sciences. The catalog number is T65704 and the CAS number is 118-29-6.
T68461	HA-118
	HA-118 is a dopamine receptor agonist.
T79202	Anticancer agent 118
	Anticancer Agent 118, an N‑acylated ciprofloxacin derivative, exhibits antibacterial efficacy against Gram-positive strains and antiproliferative effects on prostate PC3 cells, making it a potential candidate for antitum...
T82890	BFGF (119-126)
	bFGF (119-126) is a biologically active peptide corresponding to the residues of human, bovine (119-126), mouse, rat (118-125), and Heparin-Binding Growth Factor 2 (118-125) within bFGF. It functions to inhibit the dimer...
T69647	UCM-05194
	UCM-05194 is a potent Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1). UCM-05194 Shows Efficacy in Neuropathic Pain Amelioration. UCM-05194 stands out as the most potent and selective LPA1 receptor agonist de...
T75886	[Ala107]MBP(104-118) TFA
	[Ala107]MBP(104-118) TFA is a noncompetitive peptide inhibitor of protein kinase C (PKC), exhibiting IC50 values between 46-145 μM.
T79178	WRN inhibitor 2		DNA/RNA Synthesis
	WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].		DNA/RNA Synthesis
T61665	Antibacterial agent 118
	Antibacterial agent 118 (also known as compound 20) is a potent antimycobacterial compound with activity against various mycobacterial strains, including Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv, and M. avium. The mi...
T81605	Ontorpacept	TTI-621
	Ontorpacept (TTI-621) is a soluble fusion protein comprising the N-terminal (1-118) of human SIRPα fused to the Fc region of human IgG1. This N-terminal (1-118) segment serves as the binding domain for CD47, an inhibitor...
T76523	HCV Core Protein (107-114)
	HCV Core Protein (107-114), identified as the binding site within the region 101-118, is a minimally immunogenic fragment of the primary linear HCV core regions. This segment, comprising two residues that vary between ge...
T70844	CM-118
	CM-118 is a potent and selective dual inhibitor of c-Met and ALK which potently abrogates hepatocyte growth factor (HGF)-induced c-Met phosphorylation and cell migration, as well as phosphorylation of ALK, EML4-ALK, and ...
T9669	EST73502 hydrochloride
	EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with K i s of 64 nM and 118 nM for MOR and σ1R, respecti...