5-fluorouracil — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0984	5-Fluorouracil	5-FU,Fluorouracil,NSC 19893,5-Fluoracil	Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , DNA/RNA Synthesis , Endogenous Metabolite
	5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis. 5-Fluorouracil has antitumor activity and affects pyrimidine synthesis through inhibition of thymidylate synthase. 5-Fluorouracil causes apoptosis ...
T36895	5-Fluorouracil-13C,15N2	5-Fluorouracil-13C,15N2
	5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking...
T36870	5,6-dihydro-5-Fluorouracil	5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione	Others
	5,6-dihydro-5-Fluorouracil (5-FUH2) is an inactive metabolite of 5-FU and can be used for the study of organismal metabolism.		Others
T7614	Eniluracil	GW776C85,5-Ethynyluracil	Others
	Eniluracil (GW776C85) is an orally activedihydropyrimidine dehydrogenase (DPD) inhibitor,increases the oral bioavailability of 5-FU to 100%, facilitating uniform absorption and predictable toxicity.		Others
T0964	Floxuridine	5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640	Apoptosis , Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis , Antibacterial , HSV
	Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
T10013	1-Acetyl-3-o-toluyl-5-fluorouracil	A-OT-Fu	Others
	1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.		Others
T33762	Fosifloxuridine nafalbenamide	NUC-3373,NUC3373,NUC 3373	DNA/RNA Synthesis
	Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher c...		DNA/RNA Synthesis
T1307	Carmofur	HCFU	Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis
	Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
TNU1053	5-Fluorouracil-1-yl acetic acid
	5-Fluorouracil-1-yl acetic acid is a PNA-related derivative.
TNU1481	1-(b-D-Xylofuranosyl)-5-fluorouracil
	1-(b-D-Xylofuranosyl)-5-fluorouracil is a nucleoside derivative-xylo-nucleoside, fluoro-modified nucleoside, 5-modified pyrimidine nucleoside.
TNU1052	5-Fluorouracil-1-yl acetic acid methyl ester
	5-Fluorouracil-1-yl acetic acid methyl ester is a PNA-related derivative.
T1349	5-Fluorouridine		Others , DNA/RNA Synthesis
	5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound...		Others , DNA/RNA Synthesis
T27259	Emitefur	BOFA2,BOF A2,BOF-A2	Others
	Emitefur (BOF-A 2) is an orally active and potent 5-fluorouracil derivative with anticancer and antitumor activity.Emitefur is used in advanced gastric cancer, breast cancer and metabolism-related diseases.		Others
T4720	6-Hydroxypyridin-2(1H)-one hydrochloride	2,6-Dihydroxypyridine hydrochloride	Others , Endogenous Metabolite
	6-Hydroxypyridin-2(1H)-one hydrochloride (2,6-Dihydroxypyridine hydrochloride) is used as a reagent to synthesize uridine phosphorylase inhibitors that increase Uridine (Urd) (U829910) levels. Uridine is a promising bioc...		Others , Endogenous Metabolite
T1600	Doxifluridine	Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine	Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by...		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
T1408	Capecitabine	Xeloda,Capecitibine,Capiibine,RO 09-1978	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moie...
T9936	ZX-J-19J	N-(2,3-Diphenyl-6-quinoxalinyl)octanamide	Others
	ZX-J-19J (N-(2,3-Diphenyl-6-quinoxalinyl)octanamide), an inhibitor of Cyclophilin J (CyPJ), demonstrates remarkable inhibition of tumor cell growth, comparable to cyclosporine A but much stronger than 5-fluorouracil.		Others
T4374	Edoxudine	Aedurid,EUDR,Epoxudine	Antiviral , Antibacterial
	Edoxudine (Epoxudine), an antiviral drug, is an analogue of thymidine and shows effectiveness against the herpes simplex virus. Edoxudine is used as a 5-fluorouracil (FU) modulator. Edoxudine may be used to enhance the t...		Antiviral , Antibacterial
T21327	Uridine triacetate	RG 2133 triacetate,PN-401,Tri-O-acetyluridine,PN401,RG 2133,RG-2133,PN 401,RG2133,RG2133 triacetate	Others
	Uridine triacetate (RG 2133 triacetate) (Tri-O-acetyl uridine), an orally active prodrug of uridine, is efficiently absorbed in the gut and swiftly deacetylated in the circulation to release free uridine. It is utilized ...		Others
T4919	Ureidopropionic acid	Carbamoyl-b-alanine,3-Ureidopropionic acid	Endogenous Metabolite
	Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further de...		Endogenous Metabolite