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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9846 | 5-HT3 antagonist 5 | ||
5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound which is a 5-HT 3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT 3 agonist and 2-methyl-5-HT, and exhibits anti-depressant effect in mice [1]. | |||
T10162 | 5-HT3 antagonist 3 | 5-HT Receptor | |
5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM). | |||
T8438 | 4i | CHEMBL1269981,5-HT3 antagonist-4i | 5-HT Receptor |
4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system. | |||
T10051 | 5-HT3 antagonist 1 | Others | |
5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor. | |||
T5336 | Zacopride hydrochloride | Potassium Channel , 5-HT Receptor | |
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist. | |||
T6728 | VUF 10166 | 5-HT Receptor | |
VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower. | |||
T0137 | Mirtazapine | 6-Azamianserin,Org3770 | Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor |
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and h... | |||
T22016 | A-582941 dihydrochloride | A 582941 | 5-HT Receptor , AChR |
A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial | |||
T10006 | 5-HT3-In-1 | 5-HT Receptor | |
5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity. | |||
T12988 | 5-HT3 antagonist 2 | 5-HT Receptor | |
5-HT3 antagonist 2 is an antagonist of 5-HT3 receptor. | |||
T14526 | Bemesetron | TROPANYL 3,5-DICHLOROBENZOATE,3-TROPANYL-3,5-DICHLOROBENZOATE,MDL 72222 | 5-HT Receptor |
Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects. | |||
T7135 | Phenylbiguanide | PBG,N-Phenylbiguanide,1-Phenylbiguanide | 5-HT Receptor |
Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM) | |||
T1173 | Tropisetron hydrochloride | SDZ-ICS 930,Tropisetron HCl,ICS 205-930 | 5-HT Receptor |
Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activ... | |||
T8441 | Lerisetron | 5-HT Receptor | |
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity. | |||
T6616 | Ondansetron hydrochloride | SN 307,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran | 5-HT Receptor |
Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy. | |||
T1528 | Azasetron hydrochloride | Y-25130 hydrochloride,Y-25130 HCl,Azasetron HCl | 5-HT Receptor |
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic. | |||
T16433 | Pancopride | LAS 30451 | 5-HT Receptor |
Pancopride(LAS 30451) is a novel, orally available, long-acting, selective 5-HT3 receptor antagonist that blocks nitrogen mustard and dacarbazine-induced vomiting. | |||
T22448 | Tropisetron | Tropisetronum,Tropisteron,ICS 205-930 | 5-HT Receptor , AChR |
Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively. | |||
T22959 | M-Chlorophenylbiguanide hydrochloride | 1-(3-Chlorophenyl)biguanidehydrochloride | 5-HT Receptor |
5-HT3 receptor agonist | |||
T22992 | ML 10302 hydrochloride | 5-HT Receptor | |
ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of 1.07 nM and 782 nM for 5-HT4 and 5-HT3. |