Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 30.00 | |
100 mg | In stock | $ 39.00 | |
500 mg | In stock | $ 89.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 43.00 |
Description | Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM) |
Targets&IC50 | 5-HT3:3 μM (EC50) |
In vivo | Phenylbiguanide (PBG) is a drug known to stimulate cardiopulmonary afferent C-fibres. PBG is injected into the right atrium of the heart in anaesthetised mice and mapped c-Fos expression within specific regions of the central nervous system. Intraatrial injection of PBG produces a reflex cardiorespiratory response including a pronounced bradycardia and a respiratory depression[1]. |
Synonyms | PBG, N-Phenylbiguanide, 1-Phenylbiguanide |
Molecular Weight | 177.21 |
Formula | C8H11N5 |
CAS No. | 102-02-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL (846.45 mM)
You can also refer to dose conversion for different animals. More
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Phenylbiguanide 102-02-3 GPCR/G Protein Neuroscience 5-HT Receptor 5-hydroxytryptamine Receptor inhibit PBG N-Phenylbiguanide Serotonin Receptor 1-Phenylbiguanide Inhibitor inhibitor