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5-HT3 antagonist 3

Catalog No. T10162 CAS 120635-47-4

5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).

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5-HT3 antagonist 3, CAS 120635-47-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
2 mg	In stock	$ 293.00
5 mg	In stock	$ 449.00
10 mg	In stock	$ 659.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,390.00
100 mg	In stock	$ 1,880.00
500 mg	In stock	$ 3,780.00

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Purity: 99.69%

Biological Description

Chemical Properties

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Description	5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).
Targets&IC50	5-HT3 receptor:0.25 nM (ki)
In vitro	Serotonin (5-HT), involved in numerous physiological and pathophysiological processes, interacts with various distinct membrane receptors[1].

Molecular Weight	319.4
Formula	C20H21N3O
CAS No.	120635-47-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: <11 mg/mL (34.44 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. van Wijngaarden I, et al. Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. J Med Chem. 1993 Nov 12;36(23):3693-9.

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Keywords

5-HT3 antagonist 3 120635-47-4 GPCR/G Protein Neuroscience 5-HT Receptor 5 HT3 antagonist 3 5-HT-3 antagonist 3 5HT3 antagonist 3 inhibitor inhibit

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