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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5445 | 2-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi | Others | |
2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate. | |||
T5S0483 | (-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside | (-)-Syringaresnol-4-O-beta-D-apiofuranos | Others |
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) is a lignan glycosides from the bark of Albizzia myriophylla. | |||
T10938 | D-Kynurenine | (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 | GPR , AhR , Endogenous Metabolite |
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluor... | |||
T60086 | TTBK1-IN-2 | N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | Microtubule Associated |
TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 µM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures ... | |||
T77598 | Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine | (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone | Others |
Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) is a raw material for biosynthesis and can be used to synthesiz... | |||
T37835 | 2-Chloro-4-nitrophenyl-α-D-glucopyranoside | ||
Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate. For example, CNP-β-D-maltoheptaoside and CNP-α-maltotrio... | |||
T21000 | PiB | Pittsburgh Compound-B,6-OH-BTA-1 | Others |
PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis. | |||
T8940 | KUN56321 | 3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl- | Others |
KUN56321 (3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl-) is a luminescent agent. The application of KUN56321 comprises: coating the film of KUN56321 onto hole transport layer or electron transport layer of ITO g... | |||
T9779 | Protein kinase inhibitor 6 | ||
Protein kinase inhibitor 6 is a protein kinase inhibitor. | |||
T9310 | MTOR inhibitor 13 | PI3K , mTOR | |
mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively. | |||
TQ0273 | Neopterin | D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one | Endogenous Metabolite |
D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ. In humans, neopterin is involved in purine biosynthesis. | |||
TN6705 | Graveoline | 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine | Autophagy |
Graveoline (2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one) is an apoptosis and autophagy inducer in skin melanoma cancer cells | |||
T9323 | 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide | 4-Amino-6-(trifluoromethyl)benzene-1,3-d,2,4-Disulfamyl-5-trifluoromethylaniline,2-amino-4-trifluoromethyl-1,5-benzendisulfonamide | Carbonic Anhydrase |
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug. | |||
T37193 | 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside | ||
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside is a fluorogenic substrate for β-hexosaminidases. Upon enzymatic cleavage by β-hexosaminidases, 4-methylumbelliferone (4-μU) is released and its fluorescence c... | |||
T2476 | INCB032304 | 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine | Others |
INCB032304 is an important pharmaceutical intermediate. It can be used in the preparation of Ruxolitinib phosphate (I008849), a janus kinase inhibitor, and in the preparation of Barretinib. | |||
T38695 | 2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose | ||
2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose (compound 13) functions as a potent hepatic glycosaminoglycan biosynthesis inhibitor. | |||
T9585 | GNE-9815 | 3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide | Raf |
GNE-9815 (3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide) is a high kinase-selective inhibitor of RAF and targets KRAS-mutant cancers through combina... | |||
T8636 | Ibrutinib deacryloylpiperidine | IBT4A,5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine | BTK |
Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM. | |||
T25150 | BI-69A11 | BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one | NF-κB , Akt |
BI-69A11 ((E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one) is a dual AKT and NFkB pathway inhibitor. It enhances the susceptibility of colon cancer cells to mda-7/IL-24-induce... | |||
T37568 | 4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (sodium salt) | ||
4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate of heparin sulphamidase. Heparin sulphamidase cleaves 4-MU-α-GlcNS to yield 4-MU-α-GlcNH2, which is then cleaved by α... |