The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.The PROSITE pattern of this superfamily is located in a beta sheet in the central section of the protein that is conserved across all members.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPK-00591 | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)
|
Mouse | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s... | |||
TMPK-00666 | CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)
CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... | |||
TMPK-00716 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)
|
Human | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s... | |||
TMPK-00717 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s... | |||
TMPK-00727 | TNFSF12/TWEAK Protein, Human, Recombinant (hFc)
TNFSF12/TWEAK Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumula... | |||
TMPK-00860 | CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)
CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)
|
Mouse | HEK293 Cells |
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b... | |||
TMPK-01011 | TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi)
TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi)
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Mouse | HEK293 Cells |
TNFSF15 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 kDa and the ac... | |||
TMPK-01012 | TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated
|
Mouse | HEK293 Cells |
TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 ... | |||
TMPK-01013 | TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)
TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 Cells |
TNFSF15 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 48.8 kDa and the accession num... | |||
TMPK-01064 | GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)
GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 Cells |
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, pro... | |||
TMPK-01163 | APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag)
APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag)
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Mouse | HEK293 Cells |
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r... | |||
TMPK-01349 | APRIL/TNFSF13 Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag)
APRIL/TNFSF13 Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag)
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Cynomolgus | HEK293 Cells |
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r... | |||
TMPJ-01472 | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)
|
Mouse | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 23-2... | |||
TMPK-01398 | CD40 Ligand Trimer Protein, Human, Recombinant (hFc)
CD40 Ligand Trimer Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b... | |||
TMPY-00248 | Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)
Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | Baculovirus Insect Cells |
LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the... | |||
TMPY-00537 | RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc)
RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and th... | |||
TMPY-00584 | TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc)
TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession... | |||
TMPY-00618 | BAFF/TNFSF13B Protein, Canine, Recombinant (hFc)
BAFF/TNFSF13B Protein, Canine, Recombinant (hFc)
|
Canine | HEK293 Cells |
BAFF/TNFSF13B Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.5 kDa and the accessio... | |||
TMPY-00959 | 4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His)
4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the acces... | |||
TMPY-01239 | BAFF/TNFSF13B Protein, Human, Recombinant (hFc)
BAFF/TNFSF13B Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
BAFF/TNFSF13B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.7 kDa and the accession... |