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Tumor Necrosis Factor family, TNFs

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.The PROSITE pattern of this superfamily is located in a beta sheet in the central section of the protein that is conserved across all members.

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Species
Canine (4)
Cynomolgus (19)
Ferret (2)
Human (70)
Mouse (30)
Rabbit (1)
Rat (9)
Rhesus (5)
Expression System
Baculovirus Insect Cells (4)
E. coli (23)
HEK293 Cells (107)
P. pastoris (Yeast) (3)
Tag
Avi (1)
C-6xHis (3)
C-His (4)
C-His-Avi (2)
C-hFc (2)
C-mFc (1)
N-10xHis (1)
N-6xHis (5)
N-6xHis-Avi (1)
N-6xHis-Flag (3)
N-8xHis (1)
N-Avi-Fc (1)
N-Avi-hFc (3)
N-Flag (4)
N-Flag-His (1)
N-His (20)
N-His-Avi (7)
N-His-Flag (11)
N-hFc (30)
N-mFc (8)
N-monomeric hFc (2)
N-rFc (6)
Tag Free (24)
hFc (1)
Cat No. product name / Synonyms Species Expression System
TMPY-01471 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc)
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the acc...
TMPY-01594 TNF alpha Protein, Canine, Recombinant
TNF alpha Protein, Canine, Recombinant
Canine E. coli
TNF alpha Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A9LMQ0.
TMPY-01758 CD40 Ligand Protein, Human, Recombinant (His)
CD40 Ligand Protein, Human, Recombinant (His)
Human E. coli
CD40 Ligand Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.7 kDa and the accessio...
TMPY-02069 TNF alpha Protein, Cynomolgus, Rhesus, Recombinant
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant
Cynomolgus,Rhesus E. coli
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number...
TMPY-02226 TNF alpha Protein, Ferret, Recombinant
TNF alpha Protein, Ferret, Recombinant
Ferret E. coli
TNF alpha Protein, Ferret, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A3FBF1.
TMPY-02775 BAFF/TNFSF13B Protein, Human, Recombinant
BAFF/TNFSF13B Protein, Human, Recombinant
Human E. coli
BAFF/TNFSF13B Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.2 kDa and the accession number is Q9Y27...
TMPY-02784 TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His)
TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His)
Mouse E. coli
TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.2 kDa an...
TMPY-02793 CD40 Ligand Protein, Mouse, Recombinant (hFc)
CD40 Ligand Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession n...
TMPY-02944 TRAIL/TNFSF10 Protein, Rhesus, Recombinant
TRAIL/TNFSF10 Protein, Rhesus, Recombinant
Rhesus E. coli
TRAIL/TNFSF10 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.6 kDa and the accession number is F6S9...
TMPY-02992 4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (hFc)
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (hFc)
Rat HEK293 Cells
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.9 kDa and the acces...
TMPY-02993 4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (His)
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (His)
Rat HEK293 Cells
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the acces...
TMPY-03067 TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)
TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)
Rat HEK293 Cells
TL1A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is ...
TMPY-03239 CD30L Protein, Rat, Recombinant (hFc)
CD30L Protein, Rat, Recombinant (hFc)
Rat HEK293 Cells
CD30L Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the accession number is...
TMPY-03301 CD40 Ligand Protein, Rat, Recombinant (hFc)
CD40 Ligand Protein, Rat, Recombinant (hFc)
Rat HEK293 Cells
CD40 Ligand Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession num...
TMPY-03302 TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc)
TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc)
Rat HEK293 Cells
TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession n...
TMPY-03316 CD30L Protein, Cynomolgus, Recombinant (hFc)
CD30L Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
CD30L Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.1 kDa and the accession nu...
TMPY-03374 TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc)
TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc)
Human,Cynomolgus HEK293 Cells
TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.8 kDa and t...
TMPY-03527 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)
Human HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 47.9 kDa ...
TMPY-03542 CD40 Ligand Protein, Rhesus, Recombinant (hFc)
CD40 Ligand Protein, Rhesus, Recombinant (hFc)
Rhesus HEK293 Cells
CD40 Ligand Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.7 kDa and the accession ...
TMPY-03582 CD30L Protein, Rat, Recombinant
CD30L Protein, Rat, Recombinant
Rat HEK293 Cells
CD30L Protein, Rat, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.6 kDa and the accession number is A6J7Z4.
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc)
TMPY-01471
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the acc...
TNF alpha Protein, Canine, Recombinant
TMPY-01594
TNF alpha Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A9LMQ0.
CD40 Ligand Protein, Human, Recombinant (His)
TMPY-01758
CD40 Ligand Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.7 kDa and the accessio...
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant
TMPY-02069
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number...
TNF alpha Protein, Ferret, Recombinant
TMPY-02226
TNF alpha Protein, Ferret, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A3FBF1.
BAFF/TNFSF13B Protein, Human, Recombinant
TMPY-02775
BAFF/TNFSF13B Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.2 kDa and the accession number is Q9Y27...
TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His)
TMPY-02784
TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.2 kDa an...
CD40 Ligand Protein, Mouse, Recombinant (hFc)
TMPY-02793
CD40 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession n...
TRAIL/TNFSF10 Protein, Rhesus, Recombinant
TMPY-02944
TRAIL/TNFSF10 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.6 kDa and the accession number is F6S9...
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (hFc)
TMPY-02992
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.9 kDa and the acces...
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (His)
TMPY-02993
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the acces...
TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)
TMPY-03067
TL1A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is ...
CD30L Protein, Rat, Recombinant (hFc)
TMPY-03239
CD30L Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the accession number is...
CD40 Ligand Protein, Rat, Recombinant (hFc)
TMPY-03301
CD40 Ligand Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession num...
TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc)
TMPY-03302
TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession n...
CD30L Protein, Cynomolgus, Recombinant (hFc)
TMPY-03316
CD30L Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.1 kDa and the accession nu...
TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc)
TMPY-03374
TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.8 kDa and t...
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)
TMPY-03527
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 47.9 kDa ...
CD40 Ligand Protein, Rhesus, Recombinant (hFc)
TMPY-03542
CD40 Ligand Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.7 kDa and the accession ...
CD30L Protein, Rat, Recombinant
TMPY-03582
CD30L Protein, Rat, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.6 kDa and the accession number is A6J7Z4.
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