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Tumor Necrosis Factor family, TNFs

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.The PROSITE pattern of this superfamily is located in a beta sheet in the central section of the protein that is conserved across all members.

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Species
Canine (4)
Cynomolgus (19)
Ferret (2)
Human (70)
Mouse (30)
Rabbit (1)
Rat (9)
Rhesus (5)
Expression System
Baculovirus Insect Cells (4)
E. coli (23)
HEK293 Cells (107)
P. pastoris (Yeast) (3)
Tag
Avi (1)
C-6xHis (3)
C-His (4)
C-His-Avi (2)
C-hFc (2)
C-mFc (1)
N-10xHis (1)
N-6xHis (5)
N-6xHis-Avi (1)
N-6xHis-Flag (3)
N-8xHis (1)
N-Avi-Fc (1)
N-Avi-hFc (3)
N-Flag (4)
N-Flag-His (1)
N-His (20)
N-His-Avi (7)
N-His-Flag (11)
N-hFc (30)
N-mFc (8)
N-monomeric hFc (2)
N-rFc (6)
Tag Free (24)
hFc (1)
Cat No. product name / Synonyms Species Expression System
TMPY-04146 TNF alpha Protein, Human, Recombinant (hFc)
TNF alpha Protein, Human, Recombinant (hFc)
Human HEK293 Cells
TNF alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession num...
TMPY-04832 OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
OX40L/TNFSF4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa.
TMPY-02153 TNF beta Protein, Human, Recombinant
TNF beta Protein, Human, Recombinant
Human E. coli
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs ...
TMPY-01920 BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q...
TMPY-05365 BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated
Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated is expressed in HEK293 mammalian cells with AVI and Fc tag. The predicted molecular weight is ...
TMPY-03956 Fas Ligand Protein, Human, Recombinant (His)
Fas Ligand Protein, Human, Recombinant (His)
Human P. pastoris (Yeast)
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is...
TMPY-00033 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the acc...
TMPY-03364 RANKL/TNFSF11/CD254 Protein, Human, Recombinant
RANKL/TNFSF11/CD254 Protein, Human, Recombinant
Human HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is AA...
TMPJ-00137 APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
Human HEK293 Cells
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa...
TMPJ-00139 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)
Human E. coli
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16-20 KDa and...
TMPJ-00603 TL1A/TNFSF15 Protein, Mouse, Recombinant
TL1A/TNFSF15 Protein, Mouse, Recombinant
Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-sp...
TMPJ-00607 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and th...
TMPJ-00662 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
Human E. coli
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune s...
TMPJ-00779 TNF alpha Protein, Rabbit, Recombinant
TNF alpha Protein, Rabbit, Recombinant
Rabbit E. coli
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TN...
TMPJ-01391 BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
Mouse HEK293 Cells
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 45-60 KDa and the access...
TMPY-01294 TNF alpha Protein, Mouse, Recombinant
TNF alpha Protein, Mouse, Recombinant
Mouse E. coli
TNF alpha Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.39 kDa and the accession number is P06804.
TMPY-02202 TNF alpha Protein, Rat, Recombinant
TNF alpha Protein, Rat, Recombinant
Rat E. coli
TNF alpha Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is P16599.
TNF alpha Protein, Human, Recombinant (hFc)
TMPY-04146
TNF alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession num...
OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
TMPY-04832
OX40L/TNFSF4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa.
TNF beta Protein, Human, Recombinant
TMPY-02153
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs ...
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
TMPY-01920
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q...
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated
TMPY-05365
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated is expressed in HEK293 mammalian cells with AVI and Fc tag. The predicted molecular weight is ...
Fas Ligand Protein, Human, Recombinant (His)
TMPY-03956
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is...
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)
TMPY-00033
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the acc...
RANKL/TNFSF11/CD254 Protein, Human, Recombinant
TMPY-03364
RANKL/TNFSF11/CD254 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is AA...
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
TMPJ-00137
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa...
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)
TMPJ-00139
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16-20 KDa and...
TL1A/TNFSF15 Protein, Mouse, Recombinant
TMPJ-00603
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-sp...
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
TMPJ-00607
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and th...
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
TMPJ-00662
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune s...
TNF alpha Protein, Rabbit, Recombinant
TMPJ-00779
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TN...
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
TMPJ-01391
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 45-60 KDa and the access...
TNF alpha Protein, Mouse, Recombinant
TMPY-01294
TNF alpha Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.39 kDa and the accession number is P06804.
TNF alpha Protein, Rat, Recombinant
TMPY-02202
TNF alpha Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is P16599.
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