The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.The PROSITE pattern of this superfamily is located in a beta sheet in the central section of the protein that is conserved across all members.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPK-00079 | CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... | |||
TMPK-00080 | CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
|
Human | HEK293 Cells |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... | |||
TMPK-00119 | TNF alpha Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.35 kDa and the acces... | |||
TMPK-00120 | TNF alpha Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3 kDa and the a... | |||
TMPK-00121 | TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3... | |||
TMPK-00122 | CD30 Ligand/TNFSF8 Protein, Human, Recombinant (His)
CD30 Ligand/TNFSF8 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, ... | |||
TMPK-00130 | LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)
LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry m... | |||
TMPK-00140 | APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated
APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated
|
Human | HEK293 Cells |
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r... | |||
TMPK-00141 | APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag)
APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r... | |||
TMPK-00142 | APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
|
Human | HEK293 Cells |
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r... | |||
TMPK-00143 | TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)
TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)
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Human | HEK293 Cells |
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells,... | |||
TMPK-00154 | CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
|
Human | HEK293 Cells |
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b... | |||
TMPK-00171 | TRAIL Trimer Protein, Human, Recombinant (His & Flag)
TRAIL Trimer Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to it... | |||
TMPK-00174 | BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Avi), Biotinylated
BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF... | |||
TMPK-00175 | BAFF/TNFSF13B Protein, Human, Recombinant (monomeric hFc, Flag)
BAFF/TNFSF13B Protein, Human, Recombinant (monomeric hFc, Flag)
|
Human | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF... | |||
TMPK-00176 | BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)
BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF... | |||
TMPK-00489 | TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 Cells |
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells,... | |||
TMPK-00510 | BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated
BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated
|
Cynomolgus | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF... | |||
TMPK-00511 | BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi)
BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi)
|
Cynomolgus | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF... | |||
TMPK-00583 | TNF alpha Protein, Ferret, Recombinant (His)
TNF alpha Protein, Ferret, Recombinant (His)
|
Ferret | E. coli |
TNF alpha Protein, Ferret, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.88 kDa and the access... |