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Tumor Necrosis Factor family, TNFs

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.The PROSITE pattern of this superfamily is located in a beta sheet in the central section of the protein that is conserved across all members.

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Species
Canine (4)
Cynomolgus (19)
Ferret (2)
Human (70)
Mouse (30)
Rabbit (1)
Rat (9)
Rhesus (5)
Expression System
Baculovirus Insect Cells (4)
E. coli (23)
HEK293 Cells (107)
P. pastoris (Yeast) (3)
Tag
Avi (1)
C-6xHis (3)
C-His (4)
C-His-Avi (2)
C-hFc (2)
C-mFc (1)
N-10xHis (1)
N-6xHis (5)
N-6xHis-Avi (1)
N-6xHis-Flag (3)
N-8xHis (1)
N-Avi-Fc (1)
N-Avi-hFc (3)
N-Flag (4)
N-Flag-His (1)
N-His (20)
N-His-Avi (7)
N-His-Flag (11)
N-hFc (30)
N-mFc (8)
N-monomeric hFc (2)
N-rFc (6)
Tag Free (24)
hFc (1)
Cat No. product name / Synonyms Species Expression System
TMPY-03875 OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc)
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc)
Cynomolgus HEK293 Cells
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42 kDa and the accessi...
TMPY-04065 CD40 Ligand Protein, Canine, Recombinant (mFc)
CD40 Ligand Protein, Canine, Recombinant (mFc)
Canine HEK293 Cells
CD40 Ligand Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.5 kDa and the accession ...
TMPY-04086 CD40 Ligand Protein, Canine, Recombinant
CD40 Ligand Protein, Canine, Recombinant
Canine HEK293 Cells
CD40 Ligand Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16 kDa and the accession number is O97626.
TMPY-04331 LIGHT/TNFSF14 Protein, Human, Recombinant (His)
LIGHT/TNFSF14 Protein, Human, Recombinant (His)
Human HEK293 Cells
LIGHT/TNFSF14 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession...
TMPY-04354 OX40L/TNFSF4 Protein, Human, Recombinant (mFc)
OX40L/TNFSF4 Protein, Human, Recombinant (mFc)
Human HEK293 Cells
OX40L/TNFSF4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.1 kDa and the accession ...
TMPY-04581 CD30L Protein, Human, Recombinant
CD30L Protein, Human, Recombinant
Human HEK293 Cells
CD30L Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.6 kDa and the accession number is P32971.
TMPY-04587 Fas Ligand Protein, Mouse, Recombinant (His)
Fas Ligand Protein, Mouse, Recombinant (His)
Mouse P. pastoris (Yeast)
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is...
TMPY-04819 LIGHT/TNFSF14 Protein, Human, Recombinant (hFc)
LIGHT/TNFSF14 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
LIGHT/TNFSF14 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession...
TMPY-04833 LIGHT/TNFSF14 Protein, Human, Recombinant (rFc)
LIGHT/TNFSF14 Protein, Human, Recombinant (rFc)
Human HEK293 Cells
LIGHT/TNFSF14 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 45.7 kDa and the accession...
TMPY-04843 LIGHT/TNFSF14 Protein, Mouse, Recombinant (His)
LIGHT/TNFSF14 Protein, Mouse, Recombinant (His)
Mouse Baculovirus Insect Cells
LIGHT/TNFSF14 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.5 kDa and the accessi...
TMPY-04913 Fas Ligand Protein, Rat, Recombinant (His)
Fas Ligand Protein, Rat, Recombinant (His)
Rat P. pastoris (Yeast)
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is...
TMPY-04978 TL1A/TNFSF15 Protein, Human, Recombinant (rFc)
TL1A/TNFSF15 Protein, Human, Recombinant (rFc)
Human HEK293 Cells
TL1A Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 48 kDa and the accession number is ...
TMPY-04979 TL1A/TNFSF15 Protein, Human, Recombinant (mFc)
TL1A/TNFSF15 Protein, Human, Recombinant (mFc)
Human HEK293 Cells
TL1A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 47.1 kDa and the accession number i...
TMPY-04980 OX40L/TNFSF4 Protein, Mouse, Recombinant (rFc)
OX40L/TNFSF4 Protein, Mouse, Recombinant (rFc)
Mouse HEK293 Cells
OX40L/TNFSF4 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 44.4 kDa and the accession ...
TMPY-04981 OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc)
OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc)
Mouse HEK293 Cells
OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.7 kDa and the accession ...
TMPY-05041 TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc)
TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc)
Mouse HEK293 Cells
TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 43.5 kDa and the accession...
TMPY-05163 GITRL Protein, Human, Recombinant (mFc)
GITRL Protein, Human, Recombinant (mFc)
Human HEK293 Cells
GITRL Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.9 kDa and the accession number ...
TMPY-05173 4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc)
4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and th...
TMPY-05187 TNF alpha Protein, Mouse, Recombinant, Biotinylated
TNF alpha Protein, Mouse, Recombinant, Biotinylated
Mouse E. coli
TNF alpha Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession numbe...
TMPY-05237 TNF alpha Protein, Human, Recombinant, Biotinylated
TNF alpha Protein, Human, Recombinant, Biotinylated
Human E. coli
TNF alpha Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession numbe...
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc)
TMPY-03875
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42 kDa and the accessi...
CD40 Ligand Protein, Canine, Recombinant (mFc)
TMPY-04065
CD40 Ligand Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.5 kDa and the accession ...
CD40 Ligand Protein, Canine, Recombinant
TMPY-04086
CD40 Ligand Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16 kDa and the accession number is O97626.
LIGHT/TNFSF14 Protein, Human, Recombinant (His)
TMPY-04331
LIGHT/TNFSF14 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession...
OX40L/TNFSF4 Protein, Human, Recombinant (mFc)
TMPY-04354
OX40L/TNFSF4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.1 kDa and the accession ...
CD30L Protein, Human, Recombinant
TMPY-04581
CD30L Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.6 kDa and the accession number is P32971.
Fas Ligand Protein, Mouse, Recombinant (His)
TMPY-04587
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is...
LIGHT/TNFSF14 Protein, Human, Recombinant (hFc)
TMPY-04819
LIGHT/TNFSF14 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession...
LIGHT/TNFSF14 Protein, Human, Recombinant (rFc)
TMPY-04833
LIGHT/TNFSF14 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 45.7 kDa and the accession...
LIGHT/TNFSF14 Protein, Mouse, Recombinant (His)
TMPY-04843
LIGHT/TNFSF14 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.5 kDa and the accessi...
Fas Ligand Protein, Rat, Recombinant (His)
TMPY-04913
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is...
TL1A/TNFSF15 Protein, Human, Recombinant (rFc)
TMPY-04978
TL1A Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 48 kDa and the accession number is ...
TL1A/TNFSF15 Protein, Human, Recombinant (mFc)
TMPY-04979
TL1A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 47.1 kDa and the accession number i...
OX40L/TNFSF4 Protein, Mouse, Recombinant (rFc)
TMPY-04980
OX40L/TNFSF4 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 44.4 kDa and the accession ...
OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc)
TMPY-04981
OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.7 kDa and the accession ...
TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc)
TMPY-05041
TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 43.5 kDa and the accession...
GITRL Protein, Human, Recombinant (mFc)
TMPY-05163
GITRL Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.9 kDa and the accession number ...
4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc)
TMPY-05173
4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and th...
TNF alpha Protein, Mouse, Recombinant, Biotinylated
TMPY-05187
TNF alpha Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession numbe...
TNF alpha Protein, Human, Recombinant, Biotinylated
TMPY-05237
TNF alpha Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession numbe...
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TargetMol