Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinflammatory effects by inhibiting nitric-oxide (NO) production in lipopolysaccharide (LPS)-stimulated murine BV-2 microglial cells with relatively low cytotoxicity. Shizukaol B exhibits anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains, it also has significant cytotoxicities against C8166 cells. Shizukaol B prevents monocyte adhesion to HUVEC through the inhibition of cell adhesion molecules expression stimulated by TNF-alpha.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 317.00 |
Description | Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinflammatory effects by inhibiting nitric-oxide (NO) production in lipopolysaccharide (LPS)-stimulated murine BV-2 microglial cells with relatively low cytotoxicity. Shizukaol B exhibits anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains, it also has significant cytotoxicities against C8166 cells. Shizukaol B prevents monocyte adhesion to HUVEC through the inhibition of cell adhesion molecules expression stimulated by TNF-alpha. |
Source |
Molecular Weight | 732.77 |
Formula | C40H44O13 |
CAS No. | 142279-40-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Shizukaol B 142279-40-1 Apoptosis Cell Cycle/Checkpoint DNA Damage/DNA Repair GPCR/G Protein Immunology/Inflammation MAPK Microbiology/Virology Neuroscience NF-Κb Proteases/Proteasome NF-κB NOS p38 MAPK TNF IL Receptor ERK Prostaglandin Receptor JNK HIV Protease COX DNA/RNA Synthesis inhibitor inhibit