Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Ponatinib Hydrochloride is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
Description | Ponatinib Hydrochloride is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively. |
Synonyms | AP-24534, AP 24534, Ponatinib hydrochloride, AP24534 |
Molecular Weight | 569.02 |
Formula | C29H28ClF3N6O |
CAS No. | 1114544-31-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 22.5mg/mL (39.5mM), ultrasonic and warming and heat to 60°C)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Ponatinib HCl 1114544-31-8 AP-24534 Hydrochloride AP24534 Hydrochloride Inhibitor inhibitor inhibit