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Moringin

Name: Moringin
Brand: TargetMol
SKU: TN4583
Price: 118 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN4583Cas No. 73255-40-0

Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moringin has anti-inflammatory and antioxidative properties.

Moringin

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Purity: 99.97%

Catalog No. TN4583Cas No. 73255-40-0

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$118	In Stock	In Stock
5 mg	$293	In Stock	In Stock
10 mg	$468	In Stock	In Stock
25 mg	$777	-	In Stock
1 mL x 10 mM (in DMSO)	$293	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.97%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

In vitro

Moringin modulates neuroinflammation via the β-catenin-PPARγ axis and activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis. Moringin is effective in inducing apoptosis through p53 and Bax activation and Bcl-2 inhibition. Moringin demonstrates the antitumor efficacy in human malignant astrocytoma cells. The combination of Cannabidiol (5μM) and Moringin (5μM) has anti-inflammatory, antioxidative, and anti-apoptotic effects[1].

Chemical Properties

Molecular Weight	311.35
Formula	C₁₄H₁₇NO₅S
Cas No.	73255-40-0
Smiles	O([C@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O1)C2=CC=C(CN=C=S)C=C2
Relative Density.	1.42 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 62.5 mg/mL (200.74 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.42 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2118 mL	16.0591 mL	32.1182 mL	160.5910 mL
5 mM	0.6424 mL	3.2118 mL	6.4236 mL	32.1182 mL
10 mM	0.3212 mL	1.6059 mL	3.2118 mL	16.0591 mL
20 mM	0.1606 mL	0.8030 mL	1.6059 mL	8.0295 mL
50 mM	0.0642 mL	0.3212 mL	0.6424 mL	3.2118 mL
100 mM	0.0321 mL	0.1606 mL	0.3212 mL	1.6059 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc