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Moringin

Catalog No. TN4583 CAS 73255-40-0

Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moringin has anti-inflammatory and antioxidative properties.

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Moringin, CAS 73255-40-0

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Purity: 98%

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Description

In vitro

Moringin modulates neuroinflammation via the β-catenin-PPARγ axis and activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis. Moringin is effective in inducing apoptosis through p53 and Bax activation and Bcl-2 inhibition. Moringin demonstrates the antitumor efficacy in human malignant astrocytoma cells. The combination of Cannabidiol (5μM) and Moringin (5μM) has anti-inflammatory, antioxidative, and anti-apoptotic effects[1].

Molecular Weight	311.35
Formula	C14H17NO5S
CAS No.	73255-40-0

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Rajan TS, et al. Anti-inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS-stimulated macrophages. Fitoterapia. 2016 Jul;112:104-15. 2. Rajan TS, et al. Anticancer activity of glucomoringin isothiocyanate in human malignant astrocytoma cells. Fitoterapia. 2016 Apr;110:1-7.

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Keywords

Moringin 73255-40-0 DNA损伤和修复 PI3K/Akt/mTOR信号通路代谢蛋白酶体凋亡干细胞免疫与炎症神经科学细胞骨架 Nrf2 GSK-3 gp120/CD4 IL Receptor BCL Caspase COX p53 PPAR TNF Wnt/beta-catenin Inhibitor inhibitor inhibit

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