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Clioquinol

Catalog No. T0876 CAS 130-26-7

Synonyms: Chinoform, Iodochlorhydroxyquin

Clioquinol (Iodochlorhydroxyquin) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.

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Clioquinol, CAS 130-26-7

Pack Size	Availability	Price/USD
200 mg	In stock	$ 31.00
500 mg	In stock	$ 46.00
1 g	In stock	$ 53.00
5 g	In stock	$ 98.00
1 mL * 10 mM (in DMSO)	In stock	$ 48.00

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Purity: 98.09%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Clioquinol (Iodochlorhydroxyquin) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.
Cell Research	DU 145 cells are plated in a 12-well plate. After incubation for 24 h, the cells are treated with 10 μM clioquinol and 50 μM ZnCl2 for 2 h. AO is then added to each well (at a final concentration of 2.5 μg/ml). After 30 min of incubation with AO, cells are washed twice with HBSS and examined with a fluorescence microscope. (Only for Reference)

Synonyms	Chinoform, Iodochlorhydroxyquin
Molecular Weight	305.5
Formula	C9H5ClINO
CAS No.	130-26-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 1 mg/mL (3.27 mM)

DMSO: 57 mg/mL (186.6 mM)

References and Literature

1. Rohde W, et al. Antimicrob Agents ChemOthers. 1976 Aug;10(2):234-40.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Neurodegenerative Disease Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Anti-Cancer Active Compound Library Anti-Parasitic Compound Library Drug Repurposing Compound Library FDA-Approved Drug Library Autophagy Compound Library Anti-Cancer Compound Library

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Oxidopamine hydrobromide GSK3-IN-3 Doxazosin mesylate Ruxolitinib phosphate AICAR Quinacrine dihydrochloride Parthenolide AICAR phosphate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Clioquinol 130-26-7 Autophagy Microbiology/Virology Mitophagy Antibiotic Antifungal inhibit Chinoform Iodochlorhydroxyquin Inhibitor Mitochondrial Autophagy Fungal inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.