trna — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10303	Aminoacyl tRNA synthetase-IN-1		Others
	Aminoacyl tRNA synthetase-IN-1 is an inhibitor of bacterial aminoacyl tRNA synthetase (aaRS).		Others
T74612	Aminoacyl tRNA synthetase-IN-2
	Aminoacyl tRNA Synthetase-IN-2 (Compound 14) serves as an inhibitor of aminoacyl-tRNA synthetase (aaRS), presenting potential for the formulation of a novel class of antibiotics [1].
T63688	Isoleucyl tRNA synthetase-IN-1
	Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS).
T63706	Isoleucyl tRNA synthetase-IN-2
	Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).
T9533	BC-LI-0186	4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide	Others
	BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei...		Others
T9726	2’-OMe-Guanosine		Apoptosis , Nucleoside Antimetabolite/Analog
	2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.		Apoptosis , Nucleoside Antimetabolite/Analog
T41286	N6-Isopentenyladenosine		Endogenous Metabolite , Autophagy
	N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different...		Endogenous Metabolite , Autophagy
T16698	Pyronin Y	C.I. 45005,Pyronine G	Others
	Pyronin Y (Pyronine G) is an intercalating cationic dye that shows specificity towards RNA.		Others
T0895	Oxytetracycline	Terramycin	ribosome , Endogenous Metabolite , Antibacterial , Antibiotic , HSV
	Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
T6624	Oxytetracycline Dihydrate	Terramycin Dihydrate	Others , Endogenous Metabolite , Antibacterial , Antibiotic , HSV
	Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
T0788	Spectinomycin dihydrochloride	Spectinomycin 2HCl,Actinospectacin	ribosome , Antibacterial , Antibiotic
	Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.		ribosome , Antibacterial , Antibiotic
T21430	Oxytetracycline Hydrochloride	Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin	Antiviral , Endogenous Metabolite , Antibacterial , HSV
	Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin...		Antiviral , Endogenous Metabolite , Antibacterial , HSV
T6856	Halofuginone	Tempostatin,empostatin,RU-19110	Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T0788L	Spectinomycin dihydrochloride pentahydrate	Trobicin,Spectogard,Spectinomycin hydrochloride hydrate	ribosome , Antibacterial , Antibiotic
	Spectinomycin dihydrochloride pentahydrate (Spectogard) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.		ribosome , Antibacterial , Antibiotic
T3524	Halofuginone hydrobromide	Tempostatin,RU-19110 (hydrobromide),Stenorol	Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T78227	L-Methioninamide hydrochloride		DNA/RNA Synthesis
	L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP.		DNA/RNA Synthesis
T19083	1-Methylinosine	N1-Methylinosine,Inosine, 1-methyl	Nucleoside Antimetabolite/Analog , Endogenous Metabolite
	1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.		Nucleoside Antimetabolite/Analog , Endogenous Metabolite
T11919	LysRs-IN-1	9-carboxymethylguanine	Others
	LysRs-IN-1 is an inhibitor of Lysyl-tRNA synthetase (LysRs).		Others
T7514	N2-Methylguanosine		Nucleoside Antimetabolite/Analog , Endogenous Metabolite
	N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's		Nucleoside Antimetabolite/Analog , Endogenous Metabolite
T8629	N-BENZYL-2-PHENYLETHYLAMINE		Others
	N-BENZYL-2-PHENYLETHYLAMINE is an inhibitor of rel+ Escherichia coli B Phe-tRNA.		Others