substrates — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1509	Casein Kinase Substrates 3
	Casein Kinase Substrates 3 is a substrate of casein kinase.
T2011	RKI1313	RKI 1313,RKI-1313	ROCK
	RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion.		ROCK
T6941	PI-1840	PI 1840	PARP , Proteasome
	PI-1840（IC50 = 27 nM）is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).		PARP , Proteasome
T4706	Uridine-5'-diphosphate disodium salt	UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd	DNA/RNA Synthesis , Endogenous Metabolite , P2Y Receptor
	Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction...		DNA/RNA Synthesis , Endogenous Metabolite , P2Y Receptor
TD0082	EDANS sodium	EDANS sodium salt,EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt],5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt,N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Sodium Salt	Others
	EDANS sodium (5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt) is a donor for developing FRET-based nucleic acid probes that is widely used in real time PCR assays.		Others
T30677L	C15AlkOPP Tetrabutylamine salt(946615-44-7 Free base)	C15AlkOPP Tetrabutylamine salt(946615-44-7 Free base)	Others
	C15AlkOPP Tetrabutylamine salt is a “clickable” alkyne-modified analogs of the lipid substrates farnesyl diphosphate (FPP).		Others
T11221	ERAP1-IN-1		Others
	ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substrates but competitively inhibits its activi...		Others
T6945	Vps34-PIK-III	PIK-III,VPS34-IN2	PI3K , Autophagy
	Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.		PI3K , Autophagy
T9257	1,3-BUTANEDIOL		Others , Endogenous Metabolite
	1,3-Butanediol (BD) is a ketogenic substance. Ketone bodies are essential energy substrates in the absence of exogenous nutrients, and more recently, they have been suggested to prevent disease and improve longevity.		Others , Endogenous Metabolite
TN6908	Polyporusterone A	(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R,5S)-2,3-dihydroxy-5,6-dimethylheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one
	Polyporusterone A is a triterpene carboxylic acid derived from the substrates of P. umbellatus.Polyporusterone A inhibits free radical-induced erythrocyte cleavage (hemolysis), and can be used in studies of hair regenera...
T30855	CGP77675	CGP-77675,1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol,ZINC1488120,CGP 77675	EGFR , VEGFR , Bcr-Abl , Src
	CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and autophosphorylation of purified Src. CGP77675 exhibits antica...		EGFR , VEGFR , Bcr-Abl , Src
TL0009	Coniferin	Coniferoside,Abietin	Others , Antifungal
	Coniferin (Abietin) has ATP-dependent transport activity and has anti-oxidation effects. Coniferin has preferred substrates for the coniferin beta-glucosidase, the chromogenic coniferin analogue show the exclusive presen...		Others , Antifungal
T64339	Apcin A HCL		APC
	Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to...		APC
T5693	Pyrroloquinoline quinone disodium salt	Methoxatin disodium salt	Others , Endogenous Metabolite
	Pyrroloquinoline quinone disodium salt (Methoxatin disodium salt), an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a number of organic...		Others , Endogenous Metabolite
T19139	4-Nitrophenyl α-D-galactopyranoside	PNP-alpha-D-Gal,PNP-α-D-Gal	Others
	4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantl...		Others
T1757	ML-323	ML323	DUB
	ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (IC50: 174 nM 820 nM)and monoubiquitinated PCNA (Ub-PCNA) (I...		DUB
T5283	NADH disodium salt	Disodium NADH,NADH, disodium salt hydrate	Others , Endogenous Metabolite
	NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid...		Others , Endogenous Metabolite
T4904	1-Methylguanidine hydrochloride		Others , Endogenous Metabolite
	Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibit...		Others , Endogenous Metabolite
T4947	3-Hydroxybutyric acid	Butanoic acid	Endogenous Metabolite
	3-Hydroxybutyric acid (Butanoic acid) (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised in ketosis. In humans, ...		Endogenous Metabolite
T35976	6-Formylpterin
	Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photol...