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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23310 | SB-203186 hydrochloride | 5-HT Receptor | |
SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist | |||
T68087 | Inaperisone | Others | |
Inaperisone is a novel centrally acting muscle relaxant that inhibits the voiding reflex. Inaperisone may inhibit the voiding reflex by acting indirectly on GABAB receptors in the brainstem. | |||
T19723 | AMTB hydrochloride | AMTB | TRP/TRPV Channel |
AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl... | |||
T71356 | Lanperisone HCl | ||
Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK43... | |||
T72038 | YM-58790 | YM-58790 free base | AChR |
YM-58790 free base is a potent mAChR antagonist.YM-58790 free base inhibited M1 mAChR, M2 mAChR, and M3 mAChR with Ki values of 28 nM, 260 nM, and 15 nM, respectively.YM-58790 free base inhibits reflex rhythmic bladder c... | |||
T0217L | (+)-Dropropizine | (+)-Dropropizine | Histamine Receptor |
(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex and by interfering with stimulus activation of peripheral endings of sensory ... | |||
T1439 | Lacidipine | SN-305,GX-1048,GR-43659X | Apoptosis , Calcium Channel , Reactive Oxygen Species |
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi... | |||
TP2500 | Cholecystokinin (26-33) free acid | CCK (26-33) free acid | cholecystokinin |
Cholecystokinin (26-33) free acid, a part of cholecystokinin (CCK), is a highly selective ligand for CCKB-type receptors found in the vertebrate CNS and induces a mild taste aversion conditioned reflex in rats. | |||
T1229 | Erdosteine | RV 144,KW-9144 | NF-κB , Antibacterial , Adenosine deaminase |
Erdosteine (RV 144) is a homocysteine-derived thiol derivative with mucolytic and free radical scavenging properties. Erdosteine and its metabolites modulate mucus production and viscosity, by which facilitating mucocili... | |||
T10893 | CS-722 Free base | Others | |
CS-722 Free base is a synthetic central muscle relaxant with muscle relaxant activity and inhibitory effect on spinal reflex. CS-722 Free base may inhibit spontaneous inhibitory post-synaptic current and excitatory post-... | |||
T1158 | Phenoxybenzamine hydrochloride | NCI-c01661,NSC 37448,Phenoxybenzamine HCl | CaMK , Adrenergic Receptor |
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non... | |||
T24450 | Mephenoxalone | Lenetran Lenetran,TAB Lenetranat | |
Mephenoxalone is a muscle relaxant and mild anxiolytic. It inhibits neuron transmission and relaxing skeletal muscles by inhibiting the reflex arc. | |||
T40744 | Eperisone | ||
Eperisone is a centrally acting muscle relaxant and antispastic agent utilized in the treatment of conditions distinguished by muscle stiffness and pain. Its mechanism of action involves the relaxation of skeletal muscle... | |||
T28129 | Naltalimide | TRK-130,TRK 130,TRK130 | |
Naltalimide is a unique µ-opioid receptor partial agonist. Naltalimide also enhances the bladder storage function by modulating the afferent limb of the micturition reflex through µ-opioid receptors in the spinal cord. | |||
T69143 | S 332 | ||
S 332 is an adrenergic beta3-agonist that is more potent in increasing the urinary storage volume than clenbuterol and less potent in inhibiting the contractile force of urinary bladder at micturition reflex than clenbut... | |||
T37208 | NAP-1 | ||
NAP-1 is a compound with anesthetic activity.1 It increases paired-pulse inhibition in the CA1 region of rat hippocampal brain slices when used at a concentration of 100 μM. NAP-1 also induces loss of righting reflex in ... | |||
T60493 | Guaiacol Carbonate | ||
Guaiacol Carbonate is an expectorant that acts via virtue of a reflex from the stomach by way of the afferent gastric nerves to the medullary centers, then via peripherally again to the respiratory tract[1]. | |||
T29742 | AH-9700 free base | ||
AH-9700 free base is use for treatment of urge incontinence and pollakiuria.In a radioligand binding study,AH-9700 free base showed high affinities for sigma receptors and it produces a marked inhibitory effect on the mi... | |||
T73572 | NS-8 | ||
NS-8, a pyrrole derivative, activates the calcium (Ca 2+)-sensitive potassium (K+)-channel, leading to the suppression of the micturition reflex through the reduction of afferent pelvic nerve activity. This compound is v... |