postprandial — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3675	1-Deoxynojirimycin	Duvoglustat,Moranoline,moranolin	PI3K , Glucosidase
	1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.		PI3K , Glucosidase
T21344	1-Deoxynojirimycin hydrochloride	Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin	PI3K , Antibacterial , Antibiotic , Glucosidase
	1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.		PI3K , Antibacterial , Antibiotic , Glucosidase
T30142	ARRY-403	AMG-151,ARRY 403,ARRY403,ARRY-403,AMG151,AMG 151	Glucokinase
	ARRY-403 is a novel glucokinase activator that reduces fasting and postprandial blood glucose in patients with type 2 diabetes.		Glucokinase
T83969	Casein		Hydroxylase
	Casein is a milk protein with multiple roles in a novel drug delivery system that affects postprandial amino acid delivery in different ways through its intragastric coagulation properties.		Hydroxylase
T16083	Mizagliflozin	GSK-1614235 free base,KGA-3235 free base,DSP-3235 free base	SGLT
	Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that ca...		SGLT
TN1011	Rhodionin		P450 , AChE
	Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs; they can significantly suppress the elevation of ...		P450 , AChE
T2S0731	Trilobatin	P-Phlorizin	Amylase
	Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon...		Amylase
TJS0387	Desoxyrhaponticin	Deoxyrhapontin,Deoxyrhaponticin	Apoptosis , Fatty Acid Synthase
	1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least...		Apoptosis , Fatty Acid Synthase
T29448	50F10	50 F 10,50-F-10
	50F10 is a stabilizer for the active LPL dimer. It can act by preventing angptl4- and heat-induced inactivation of LPL and reducing postprandial triglyceride levels.
T30118	Arbaclofen placarbil	XP 19986,XP19986,XP-19986
	Arbaclofen placarbil( XP19986) is a GABA(B) receptor agonist.Arbaclofen Placarbil is a novel R-baclofen prodrug with improved absorption, distribution, metabolism, and elimination properties compared to R-baclofen. And i...
TP1566	GIP (1-30) amide (Human) (TFA)
	GIP (1-30) amide (Human) TFA is a glucose-dependent insulinotropic polypeptide fragment. Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone that stimulates insulin secretion and reduces postprandia...
T71340	Mizagliflozin sebacate
	Mizagliflozin sebacate is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from...
T25375	Enprostil	RS-84135,RS 84135,Gardrin,RS84135
	Enprostil is a synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on gastrin. It has efficient and safe in the therapy of gastroduod...
T29154	WB403	WB-403,WB 403
	WB403 is a TGR5 activator. WB403 significantly decreases fasting blood glucose, postprandial blood glucose and HbA1c, improves glucose tolerance in type 2 diabetic mice. WB403 increases pancreatic β-cells and restores th...
T26718	AZD6370	AZD-6370,AZD 6370
	AZD-6370 is a glucokinase activator. AZD-6370 decreases fasting and postprandial glucose in type 2 diabetes mellitus patients with effects influenced by dosing regimen and food. AZD-6370 do not affect the central counter...
T6203L	Saxagliptin hydrochloride	BMS477118,Saxagliptin,BMS 477118,Saxagliptin HCl,BMS-477118
	Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fas...
T72909	D-(+)-Sorbose
	D-(+)-Sorbose, the active enantiomer of D-Sorbose, inhibits disaccharidase activity and demonstrates suppressive effects on postprandial blood glucose and insulin levels in rats. Its role as a sweetener may aid in preven...
T14382	AZD7687		Others
	AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial...		Others
T80007	Stevisalioside A		Phosphatase
	Stevisalioside A (Compound 2), isolated from the roots of Stevia serrata, is an orally active antidiabetic agent that inhibits Protein Tyrosine Phosphatase 1B (PTP1B) with an IC50 value of 526.8 μM. It effectively lowers...		Phosphatase
T35798	Massarigenin C
	Massarigenin C is a fungal metabolite that has been found inM. flavoroseaand has enzyme inhibitory activities.1,2Massarigenin C inhibits neuraminidasein vitro(IC50= 4.15 μM).2It is also an inhibitor of yeast α-glucosidas...