permeant — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7736	2-Chloroadenosine		Adenosine Receptor
	2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively)		Adenosine Receptor
T21627	Hoechst 33342 trihydrochloride	HOE 33342 trihydrochloride,bisBenzimide H 33342 trihydrochloride,bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride,Hoechst 33342	Others , Autophagy
	Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.		Others , Autophagy
T12205	Ned 19		Calcium Channel
	Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in mice.		Calcium Channel
T7658	Dimethyl DL-Glutamate (hydrochloride)		Others
	Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes.		Others
T2449	D4476	D 4476,Casein Kinase I Inhibitor	Apoptosis , Casein Kinase , ALK , Autophagy
	D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).		Apoptosis , Casein Kinase , ALK , Autophagy
T17109	TMRM Perchlorate	T668	Others
	TMRM Perchlorate (T668) is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm).		Others
TP1907L1	Dynamin inhibitory peptide, myristoylated acetate	Dynamin inhibitory peptide, myristoylated acetate(251634-22-7 free base)	Dynamin
	Dynamin inhibitory peptide, myristoylated acetate is a DynaMin inhibitor to interfere with the binding of amphiphysin with dynamin. DynaMin inhibitory peptide, myristoylated TFA is a membrane-permeant form of the peptide...		Dynamin
T6573	E 64c	NSC 694279,EP 475,Loxistatin Acid	SARS-CoV , Cysteine Protease
	E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.		SARS-CoV , Cysteine Protease
T2606	KN-93 Phosphate		CaMK
	KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II with K i of 370 nM. KN-93 phosphate inhibits serum-induced fibroblast cell growth in a comparable dose-dependent fashion to it...		CaMK
T14048	5-CFDA	5-Carboxyfluorescein diacetate	Others
	5-CFDA (5-Carboxyfluorescein diacetate)(5-Carboxyfluorescein diacetate) is membrane-permeant. It can be loaded into cells via incubation and hydrolyzed by intracellular esterases to 5-carboxyfluorescein that is used for ...		Others
T9807	CPDS		Others
	CPDS is a non permeant thiol agent which affects several mitochondrial functions. In rat liver mitochondria, CPDS inhibits only the Pi/OH- carrier; both CPDS and n-butylmalonate are necessary to inhibit completely Pi ent...		Others
T18894	5(6)-CFDA	CFDA,5-(6)-Carboxyfluorescein diacetate	Others
	5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activities, which is required to activate its fluorescence, and cell-m...		Others
T13884	Shield-1		Others
	Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused protein...		Others
T34706	SRI-29132	SRI29132,SRI 29132,TPZ-11,TPZ 11,TPZ11
	SRI-29132 is potent; highly permeant of the blood-brain barrier; and selective for LRRK2 kinase activity, therefore effective in attenuating pro-inflammatory responses in macrophages and in rescuing neurite retraction ph...
T17109L	TMRM		Others
	TMRM is a cell-permeant cationic lipophilic red fluorescent dye (λex: 530 nm, λem: 592 nm).		Others
T69514	CLE-030
	CLE-030 is a KCNQ2 agonist. CLE030 stably binds to the central cavity. Functional analysis, molecular dynamics simulations, and calculations of the potential of mean force revealed that the carbonyl oxygen of CLE030 inf...
T37477	L-858,051 (hydrochloride)
	L-858,051 is a water-soluble analog of forskolin , a cell-permeant activator of adenylate cyclase. L-858,051 activates adenylate cyclase (EC50 = 3 μM), inhibits glucose transport, and blocks cytochalasin B binding in rat...
T37473	SBFI AM	Sodium-binding Benzofuran Isophthalate Acetoxymethyl ester
	SBFI AM is a membrane-permeant, fluorescent Na+ indicator dye. It is selective for Na+ over K+ with Kd values of 20 and 120 mM for these ions, respectively. [1]Increasing concentration of Na+ increases the ratio of excit...
T37607	Rhodamine B isothiocyanate (mixed isomers)
	Rhodamine B isothiocyanate (RITC) is a cell-permeant fluorogenic dye most often used as a conjugate to antibodies and proteins for fluorescence detection in microscopy. It displays excitation/emission maxima of 570/595 n...
T36327	Calcein Red™ AM
	Calcein Red AM is a fluorogenic dye that is used to assess cell viability. As the acetoxymethyl ester, Calcein Red AM is non-fluorescent but cell-permeant and is hydrolyzed to the fluorescent probe Calcein Red by intr...