keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TMRM Perchlorate (T668) is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 64.00 | |
25 mg | In stock | $ 123.00 | |
50 mg | In stock | $ 228.00 | |
100 mg | In stock | $ 372.00 | |
200 mg | In stock | $ 517.00 | |
500 mg | In stock | $ 838.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 43.00 |
Description | TMRM Perchlorate (T668) is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm). |
In vitro | TMRM Perchlorate is a fluorescent probe (excitation, 530±21 nm; emission, 592±22 nm). The fluorescence signal in the presence of TMRM Perchlorate shows a slight decrease after the addition of glutamate, indicative of increased polarization of the mitochondrial inner membrane. In the presence of TMRM Perchlorate (2 μM) the coupled respiration with Complex I substrates or upon the addition of Complex II substrate is decreased by 27%[1]. Exposure of hippocampal cultures to low concentrations of TMRM Perchlorate (50 to 500 nM) for 1 to 3 hours results in selective staining of mitochondria in both neurons and the underlying glial cells. Exposure of hippocampal cultures to high concentrations of TMRM Perchlorate (1 to 25 μM) stains mitochondria selectively and quickly, reaching a plateau after 5 to 10 min. Low concentrations of TMRM Perchlorate (50 to 200 nM) do not induce apoptosis, whereas higher concentrations (0.5 and 2.5 μM) enhance apoptosis (KD?=?500 nM)[2]. |
Synonyms | T668 |
Molecular Weight | 500.93 |
Formula | C25H25ClN2O7 |
CAS No. | 115532-50-8 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 41.67 mg/mL (83.19 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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TMRM Perchlorate 115532-50-8 Others T 668 TMRM T-668 T668 inhibit Inhibitor inhibitor