oxide — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T20936	Lauramine oxide	LDAO,Dimethylaurylamine oxide,Refan,Lauryldimethylamine oxide	Antibacterial
	Lauramine oxide (Refan) is effective against common bacteria such as E. coli and S. aureus, however it is non-denaturing and may be used to solubilize proteins.		Antibacterial
T23636	Adenosine N1-oxide	ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide	Immunology/Inflammation related
	Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock.		Immunology/Inflammation related
T0617	Nicotinamide N-oxide	Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide	c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite
	Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n...		c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite
T35366	4-Nitroquinoline 1-oxide	4-Nitroquinoline 1-oxide,4Nqo,NQO,4-NQO,4-Nitroquinoline-N-oxide,NQNO	Others
	4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts of purine adducts.		Others
T0067	Nicotinic acid N-oxide	Nicotinic acid 1-oxide,Oxiniacic Acid	Others
	Nicotinic acid N-oxide (Nicotinic acid 1-oxide) is a nicotinic acid derivative, used to treat hyperlipoidemia.		Others
T2724	Caryophyllene oxide		Others , Endogenous Metabolite
	Caryophyllene oxide is isolated from Aegle marmelos, with anti-inflammatory activity.		Others , Endogenous Metabolite
T0621	Diphenyl oxide	Oxydibenzene,Phenyl ether	Others
	Diphenyl oxide (Oxydibenzene) is used in the manufacture of spices and dyes.		Others
T41245	Trimethylamine N-oxide		Reactive Oxygen Species , NOD-like Receptor (NLR) , TGF-beta/Smad
	Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline, betaine, and carnitine via intestinal microbial metabolism that accumulates in tissues of marine animals and prevents the protein-damaging e...
T37600	Dasatinib N-oxide		Others
	Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib.It is also a potential impurity in commercial preparations of dasatinib[1][2].		Others
T9433	Nickel(II) oxide		Others
	Nickel(II) oxide is the chemical compound with the formula NiO. It is the principal oxide of nickel.		Others
T38003	Levofloxacin N-oxide		Others
	Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin . Levofloxacin N-oxide is also a degradation product of levofloxacin that is formed through exposure to daylight or hydrogen peroxide.		Others
T28231	Olanzapine N-Oxide		Others
	Olanzapine N-Oxide is a metabolite of Olanzapine which shows antipsychotic activity.		Others
TN7068	Sinomenine N-oxide		Others
	Sinomenine N-oxide is one of the major metabolites of the cyclic metabolic mechanism of Sinomenine.		Others
T4462	Roflumilast N-oxide		PDE
	Roflumilast N-oxide is an inhibitor of PDE type 4.		PDE
T11351	Galanthamine N-Oxide		AChE
	Galanthamine N-Oxide, an alkaloid extracted from Zephyranthes concolor bulbs, effectively inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of 26.2 μM. It acts as a significant inhibitor of substrate ac...		AChE
T19433	Monocrotaline N-Oxide		Others
	Monocrotaline N-Oxide is a monocrotaline metabolite.		Others
T0636	4-Methylmorpholine N-oxide		Others
	4-Methylmorpholine N-oxide is often used as a co-oxidant and sacrificial catalyst in oxidation reactions.		Others
T72112	Clozapine N-oxide dihydrochloride		AChE
	Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs) that crosses the blood-brain barrier.Clozapine N-oxide dihydrochloride induces activation of DR...		AChE
T4494	CLOZAPINE N-OXIDE		Dopamine Receptor , 5-HT Receptor , AChR , Drug Metabolite
	Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopa...		Dopamine Receptor , 5-HT Receptor , AChR , Drug Metabolite
T5247	Trimethylamine N-oxide dihydrate	TMANO Dihydrate	Others , Endogenous Metabolite
	Trimethylamine N-oxide dihydrate (TMANO Dihydrate), a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.		Others , Endogenous Metabolite