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Galanthamine N-Oxide

Catalog No. T11351 CAS 134332-50-6

Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes. Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor.

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Galanthamine N-Oxide, CAS 134332-50-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes. Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor.
Targets&IC50	AChE:EC50 of 26.2 μM

Molecular Weight	303.35
Formula	C17H21NO4
CAS No.	134332-50-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 55 mg/ml (181.31 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

2. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Galanthamine N-Oxide 134332-50-6 Neuroscience AChE Inhibitor substrate Galanthamine N Oxide Galanthamine NOxide alkaloid site active accommodation Cholinesterase (ChE) inhibit inhibitor

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