15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2786 | Oxysophocarpine | Prostaglandin Receptor | |
Oxysophocarpine is extracted from Sophra flavescens Ait. | |||
T27242 | EF24 | EF 24,EF-24,3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone | ERK , MEK , Caspase |
EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral ... | |||
TN3726 | Cudraflavone B | IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy | |
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mouse melanoma cells, and hepatoprotective activity. It may b... | |||
T27711 | Kahweol Eicosanate | J002075,J 002075,J-002075 | |
Kahweol Eicosanate is a semi-syntetic derivative of kahweol. Kahweol Eicosanate exhibits a wide variety of biological activities, including inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, ... | |||
T71479 | Kahweol oleate | ||
Kahweol oleate is emi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell ... | |||
T71480 | Kahweol linoleate | ||
Kahweol linoleate is a semi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing... | |||
T68641 | Kahweol Acetate | ||
Kahweol Acetate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing ... | |||
T35821 | CAY10721 | ||
CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph no... | |||
T68642 | Kahweol palmitate | ||
Kahweol palmitate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducin... | |||
T71478 | Kahweol stearate | ||
Kahweol stearate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing... | |||
T16354 | NSC745885 | Others | |
NSC745885 is an effective down-regulator of EZH2 via proteasome-mediated degradation. NSC745885 is also an effective anti-tumor agent that displays selective toxicity against multiple cancer cell lines but not normal cel... | |||
T73662 | Peplomycin | ||
Peplomycin (Bleomycin PEP; Pepleomycin), an analogue of Bleomycin, exhibits significant antitumor activity with reduced pulmonary toxicity. It induces apoptosis in the oral squamous carcinoma cell line SSCKN and causes p... | |||
T79602 | MTP | Autophagy | |
MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation. Further, it inhibits JAK2 signaling, rendering it useful for the study of ora... | |||
T36844 | Inostamycin A | ||
Inostamycin A is a bacterial metabolite that has been found inStreptomycesand has anticancer activity.1It is an inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase (IC50= 0.02 μg/ml in A431 cell membranes)... | |||
T35426 | β-Defensin-1 (human) (trifluoroacetate salt) | ||
β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus... |