Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 33.00 | |
5 mg | In stock | $ 76.00 | |
10 mg | In stock | $ 133.00 | |
25 mg | In stock | $ 283.00 | |
50 mg | In stock | $ 455.00 | |
100 mg | In stock | $ 672.00 | |
500 mg | In stock | $ 1,430.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 84.00 |
Description | EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway. |
Synonyms | EF 24, EF-24, 3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone |
Molecular Weight | 311.33 |
Formula | C19H15F2NO |
CAS No. | 342808-40-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10mg/mL
You can also refer to dose conversion for different animals. More
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EF24 342808-40-6 Apoptosis MAPK Proteases/Proteasome MEK Caspase ERK EF 24 inhibit EF-24 Inhibitor Extracellular signal regulated kinases 3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone inhibitor