oral — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12316	Oral antiplatelet agent 1		Others
	Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro.		Others
T20764	Dienestrol diacetate	NSC 81279,NSC81279,Cycladiene,Retalon-oral,Oestrasid C,NSC-81279
	Dienestrol diacetate, a derivative of the synthetic non-steroid phenolic compound, DIENESTROL, exhibits estrogenic activities.
T19858	Brodimoprim		DHFR , Antibacterial
	Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR). Brodimoprim is also a long-acting broad-spectrum antibacterial agent characterized by a good pharmacokinetic profile.		DHFR , Antibacterial
T9680	Irloxacin		Antibacterial
	Irloxacin is a new quinolone derivative, and shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria.		Antibacterial
T10423	AWZ1066S		Parasite
	AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).		Parasite
T8850	Sbp-7455		Autophagy
	SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.		Autophagy
T22341	GSK-114		Others
	GSK-114, a selective inhibitor of TNNI3 Interacting Kinase (TNNI3K) with IC50 of 25 nM, shows significant bias for TNNI3K over B-Raf with IC50 of 1000 nM, exceptional broad spectrum kinase selectivity and adequate oral e...		Others
T11689	ITI-214	ITI214	PDE
	ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ...		PDE
T9706	BTK inhibitor 17		BTK
	BTK inhibitor 17 is a potent irreversible BTK inhibitor (IC50 = 2.1 nM). BTK inhibitor 17 can be used in rheumatoid arthritis studies.		BTK
T9121	AG-636		Dehydrogenase , DNA/RNA Synthesis
	AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.		Dehydrogenase , DNA/RNA Synthesis
T41277	PACMA 31		Others
	PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.		Others
T31976	Glymidine sodium		Others
	Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion.		Others
T5477	ELQ-300		Parasite
	ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1)		Parasite
T9452	PW0787		GPR
	PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM).		GPR
T20525	Chloramphenicol palmitate		Antibacterial , Antibiotic
	Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in tra...		Antibacterial , Antibiotic
T7436	Cilofexor		FXR , Autophagy
	Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.		FXR , Autophagy
T16777	ROC-325		Apoptosis , Autophagy
	ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity.		Apoptosis , Autophagy
T14358	Avoralstat	BCX4161	Others
	Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.		Others
T5513	RO-3		P2X Receptor
	RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor		P2X Receptor
T11723L	JNJ-39758979		Histamine Receptor
	JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine...		Histamine Receptor