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Search Results for " mycobacterial "

20

Compounds

Cat No. Product Name Synonyms Targets
T72306 Mycobacterial Zmp1-IN-1
Mycobacterial Zmp1-IN-1, a zinc metalloprotease-1 (Zmp1) inhibitor, demonstrates dose-dependent anti-mycobacterial activity against Mtb H37Ra, making it suitable for tuberculosis (TB) research.
TN1040 Skullcapflavone II COX , Antibacterial , TGF-beta/Smad
Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavone II may have therapeutic potential for the treatment of al...
T16339 Norverapamil hydrochloride (±)-Norverapamil hydrochloride,D591 hydrochloride Calcium Channel , P-gp , Drug Metabolite
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
T10662L Calcimycin Antibiotic A-23187,A-23187 Apoptosis , Antibacterial , Antibiotic , Autophagy , Antifungal
Calcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes and uncouples oxidative phosphorylatio...
T60073 Antimycobacterial agent-4 4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide Antibacterial
Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) has antibacterial activity against Mycobacterium tuberculosis.
T63420 Antimycobacterial agent-2
Antimycobacterial agent-2 is an effective anti-mycobacterial agent with a MIC99 of 0.8 μM against Mycobacterium tuberculosis (M.tb) H37Rv. Antimycobacterial agent-2 is cytotoxic, acting on CHO cells (IC50: 48.1 μM).
T61853 Antimycobacterial agent-1
Antimycobacterial agent-1 (compound 33) demonstrates potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra, with a minimal inhibitory concentration (MIC) value of 1 μg/ml. Notably, antimycobacterial ...
T79281 Antimycobacterial agent-6
Antimycobacterial agent-6 (compound 25) effectively inhibits Mycobacterium tuberculosis, including wild-type and fluoroquinolone-resistant strains, by targeting the Mtb DprE1-C387S mutant. It displays minimal inhibitory ...
T63865 Antimycobacterial agent-3
Antimycobacterial agent-3 is an antimycobacterial agent with low cytotoxicity. antimycobacterial agent-3 is effective against sensitive MTB strain H37Rv and resistant clinical isolates (MIC < 0.029-0.110 μ M).
T4S1545 Licarin B (-)-Licarin B,Licarine B transporter , Antibacterial , PPAR
1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.
T8229 5,7,3',4'-Tetramethoxyflavone Antibacterial , Parasite , Antifungal
5,7,3',4'-Tetramethoxyflavone (TMF), a prominent polymethoxyflavone (PMF) derived from M. exotica, displays a range of notable bioactivities. These include anti-malarial, anti-fungal, anti-mycobacterial, and anti-inflamm...
T78748 MtUng-IN-1 Antibacterial
MtUng-IN-1 (Compound 18a) inhibits mycobacterial uracil DNA glycosylase (MtUng) with an IC50 value of 300 μM. MtUng-IN-1 is suitable for use in cancer and infectious disease research.
T12231 NITD-349 Others , Antibacterial
NITD-349 is an inhibitor of MmpL3. It shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv.
T8411 C-215 Others
C-215 is a novel inhibitor of mycobacterial membrane protein large 3 (MmpL3).
T0377 Clofazimine NSC-141046 DNA , Antibacterial , Antibiotic
Clofazimine (NSC-141046) is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria.
T2585 Bedaquiline R207910,TMC207 Antibacterial , Antibiotic
Bedaquiline (R207910)(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculo...
TN1594 DL-Syringaresinol (±)-Syringaresinol Antioxidant , Antifungal
DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin agi...
T29249 (+)-Xylariamide A Xylariamide-A,ent Xylariamide A,ent-Xylariamide A,Xylariamide A
(+)-Xylariamide A is a probe used for mycobacterial and fungal carbonic anhydrase.
T10563 BM635 Others
BM635 is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).
T61676 4-Piperidinecarboxamide
4-Piperidinecarboxamide is a mycobacterial aspartyl-tRNA synthetase (AspS) inhibitor and a potential anti-tuberculosis (TB) agent [1].
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