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20

Compounds

Cat No. Product Name Synonyms Targets
T10096L Voruciclib CDK
Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the ...
T7512 BMS-191011 BMS-A Potassium Channel
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
T10774 CFM-2 iGluR
CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models.
T14127 Adenosine A1 receptor activator T62 Adenosine Receptor
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve...
T61151 Beclobrate
Beclobrate (Sgd 24774), a fibric acid derivative, exhibits potent lipid-lowering efficacy in rodent models [1].
T11121 Duoperone Others
Duoperone is a neuroleptic agent. Duoperone shows antiemetic activity in animal models.
T26091 Riparin III
Riparin III is an alcamide isolated from Aniba riparia that has exhibited effects of antidepressant and anxiolytic activities in acute stress behavioral models.
T28217 NTRC-844 NTRC 844,NTRC844 Neurotensin Receptor
NTRC-844 is a selective rat neurotensin receptor type 2 (NTS2) antagonist that shows analgesic activity in animal models of pain.
T34656 SKLB 1028 Ruserontinib EGFR , FLT , Bcr-Abl
SKLB 1028 (Ruserontinib) is a new type of oral multikinase inhibitor of EGFR, FLT3, and Abl. SKLB 1028 shows excellent activity in FLT3-driven AML models and considerable potency in CML models containing Abl mutants.
T21609L Beta-Sheet Breaker Peptide iAβ5 Acetate Beta-Sheet Breaker Peptide iAβ5 Acetate(182912-74-9 Free base) Others
Beta-Sheet Breaker Peptide iAβ5 Acetate (C33H43N5O8) inhibit amyloidogenesis in rat brain models.
T35187 XR 5944 XR-5944,MLN-944,MLN944,XR5944,MLN 944
XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models.
T4335 GNE-617 GNE617 NAMPT
GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.
T27400L Ganaplacide phosphate Ganaplacide phosphate (1261113-96-5 Free base) Others
Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models.
T23717 Ameltolide Others
Ameltolide is an anticonvulsant agent. It has been shown to be effective at inhibiting seizures in animal models.
T6896 Tolimidone NSC 314335,MLR-1023,CP-26154 Src
Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
T8318 BNC210 H-Ile-Trp-OH,IW-2143 AChR
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
T22595 B2 Linazolamide intermediate B impurity 2,CPNQ,5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline Others , Sirtuin
B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease
T18976 Dihydrofluorescein diacetate Diacetyldihydrofluorescein Others
Dihydrofluorescein diacetate (Diacetyldihydrofluorescein) is a fluorescent probe for measuring oxidative stress in cell-free systems and cellular models.
T13774 ML390 Others , Dehydrogenase
ML390 exerts its potent differentiation effect on multiple leukemia models.
T1860 Imepitoin AWD 131-138,ELB-138 GABA Receptor
Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.
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