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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10096L | Voruciclib | CDK | |
Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the ... | |||
T7512 | BMS-191011 | BMS-A | Potassium Channel |
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models | |||
T10774 | CFM-2 | iGluR | |
CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models. | |||
T14127 | Adenosine A1 receptor activator T62 | Adenosine Receptor | |
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve... | |||
T61151 | Beclobrate | ||
Beclobrate (Sgd 24774), a fibric acid derivative, exhibits potent lipid-lowering efficacy in rodent models [1]. | |||
T11121 | Duoperone | Others | |
Duoperone is a neuroleptic agent. Duoperone shows antiemetic activity in animal models. | |||
T26091 | Riparin III | ||
Riparin III is an alcamide isolated from Aniba riparia that has exhibited effects of antidepressant and anxiolytic activities in acute stress behavioral models. | |||
T28217 | NTRC-844 | NTRC 844,NTRC844 | Neurotensin Receptor |
NTRC-844 is a selective rat neurotensin receptor type 2 (NTS2) antagonist that shows analgesic activity in animal models of pain. | |||
T34656 | SKLB 1028 | Ruserontinib | EGFR , FLT , Bcr-Abl |
SKLB 1028 (Ruserontinib) is a new type of oral multikinase inhibitor of EGFR, FLT3, and Abl. SKLB 1028 shows excellent activity in FLT3-driven AML models and considerable potency in CML models containing Abl mutants. | |||
T21609L | Beta-Sheet Breaker Peptide iAβ5 Acetate | Beta-Sheet Breaker Peptide iAβ5 Acetate(182912-74-9 Free base) | Others |
Beta-Sheet Breaker Peptide iAβ5 Acetate (C33H43N5O8) inhibit amyloidogenesis in rat brain models. | |||
T35187 | XR 5944 | XR-5944,MLN-944,MLN944,XR5944,MLN 944 | |
XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models. | |||
T4335 | GNE-617 | GNE617 | NAMPT |
GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer. | |||
T27400L | Ganaplacide phosphate | Ganaplacide phosphate (1261113-96-5 Free base) | Others |
Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models. | |||
T23717 | Ameltolide | Others | |
Ameltolide is an anticonvulsant agent. It has been shown to be effective at inhibiting seizures in animal models. | |||
T6896 | Tolimidone | NSC 314335,MLR-1023,CP-26154 | Src |
Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals. | |||
T8318 | BNC210 | H-Ile-Trp-OH,IW-2143 | AChR |
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression. | |||
T22595 | B2 | Linazolamide intermediate B impurity 2,CPNQ,5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline | Others , Sirtuin |
B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease | |||
T18976 | Dihydrofluorescein diacetate | Diacetyldihydrofluorescein | Others |
Dihydrofluorescein diacetate (Diacetyldihydrofluorescein) is a fluorescent probe for measuring oxidative stress in cell-free systems and cellular models. | |||
T13774 | ML390 | Others , Dehydrogenase | |
ML390 exerts its potent differentiation effect on multiple leukemia models. | |||
T1860 | Imepitoin | AWD 131-138,ELB-138 | GABA Receptor |
Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models. |