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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4S0051 | Coptisine sulfate | Indoleamine 2,3-Dioxygenase (IDO) | |
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program. | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
T11615 | IDO-IN-12 | IDO , Indoleamine 2,3-Dioxygenase (IDO) | |
IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO). | |||
T3S1967 | (S)-Indoximod | N-ME-Tryptophan,Abrine,L-Abrine | Others , Indoleamine 2,3-Dioxygenase (IDO) |
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L... | |||
T11901 | IDO1-IN-5 | IDO , Indoleamine 2,3-Dioxygenase (IDO) | |
IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. | |||
T11616 | IDO-IN-13 | GS-4361 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
IDO-IN-13 (GS-4361) is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM). | |||
T9164 | BMS-986242 | BMS986242 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer. | |||
T10199 | GNF-PF-3777 | 8-Nitrotryptanthrin | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
GNF-PF-3777 (8-Nitrotryptanthrin) (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM). | |||
T2647 | IDO5L | INCB024360 analogue,INCB14943 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM). | |||
T4532 | Linrodostat | BMS-986205 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor. | |||
TQ0071 | Navoximod | GDC-0919,NLG-919 | Indoleamine 2,3-Dioxygenase (IDO) |
Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM). | |||
T4307 | PF-06840003 | EOS200271,PF 06840003 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor. | |||
T7181 | IDO-IN-1 | Indoleamine 2,3-Dioxygenase (IDO) | |
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.) | |||
T3548 | Epacadostat | INCB 024360,IDO Inhibitor 1 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
Epacadostat (INCB 024360) is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reducing tumor-associated regulatory T cells. | |||
T1847 | Necrostatin-1 | Nec-1,Necrostatin 1 | Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase |
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO. | |||
T2718 | Palmatine chloride | Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase | |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |||
T4142 | PCC0208009 | IDO inhibitor 1,DO-IN-2,IDO-IN-2 | Indoleamine 2,3-Dioxygenase (IDO) |
PCC0208009 (IDO-IN-2) is an IDO inhibitor. | |||
T5S0056 | Coptisine chloride | Q-100696,NSC-119754 | Indoleamine 2,3-Dioxygenase (IDO) , Influenza Virus , Antibacterial |
1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds. | |||
T5S0802 | Palmatine | Berbericinine,Burasaine | Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase |
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,... | |||
T1806 | IDO-IN-7 | NLG919,Navoximod,NLG-919 analogue,GDC-0919 | Indoleamine 2,3-Dioxygenase (IDO) |
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor. |