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Metabolism IDO BMS-986242

BMS-986242

Catalog No. T9164   CAS 1923844-48-7
Synonyms: BMS 986242, BMS986242,

BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.

BMS-986242, CAS 1923844-48-7
Pack Size Availability Price/USD Quantity
1 mg In stock 228.00
5 mg In stock 484.00
10 mg In stock 845.00
25 mg In stock 1783.00
50 mg In stock 2783.00
100 mg In stock 4323.00
1 mL * 10 mM (in DMSO) In stock 496.00
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Purity 98.25%
Biological Description
Chemical Properties
Storage & Solubility Information
Description BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.
In vivo BMS-986242 (3~30 mg/kg; p.o.; 0~24 hours) shows dose-proportional exposure and a statistically significant reduction in kynurenine concentration in the tumor at all three doses
Synonyms BMS 986242 , BMS986242 ,
Purity 98.25%
Molecular Weight 410.91
Formula C24H24ClFN2O
CAS No. 1923844-48-7

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: 250 mg/mL (608.41 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Cherney EC, et al. Discovery and Preclinical Evaluation of BMS-986242, a Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1. ACS Med Chem Lett. 2021;12(2):288-294. Published 2021 Jan 28.

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IDO1-IN-1 IDO1-IN-5 Navoximod GNF-PF-3777 IDO-IN-12 IDO-IN-9 IDO-IN-3 IACS-8968

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.