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19

Compounds

Cat No. Product Name Synonyms Targets
T1602 Valproic acid sodium salt Sodium Valproate Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha...
T7064 Valproic Acid Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
T6474 Divalproex Sodium Valproate semisodium,Epival HDAC
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...
T68067L Etilefrine pivalate HCl Etilefrine pivalate HCl(100696-30-8 Free base)
Etilefrine pivalate HCl is an orally active compound for the treatment of migraine headaches.
T68145 Stacofylline
Stacofylline is a xanthine derivative that is used to treat migraine headaches.
T76682 Galcanezumab LY 2951742 CGRP Receptor
Galcanezumab is a humanized IgG4 monoclonal antibody targeting the CGRP ligand, which binds to the ligand calcitonin gene-related peptide. Galcanezumab can be used to prevent and treat migraines or cluster headaches.
T8666 Naratriptan 5-HT Receptor
Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.
T1092 Zolmitriptan 311C90,BW-311C90 5-HT Receptor
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and...
T1512 Rizatriptan benzoate MK-462 Benzoate 5-HT Receptor
Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches.
T0246L Betahistine mesylate Extovyl,Melopat,Meginalisk Histamine Receptor
Betahistine mesylate (Extovyl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers.
T4195 Betahistine PT 9 base,Vasomotal,Serc base Histamine Receptor
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti...
T0976 Propoxur Aprocarb,Propoxure,Baygon AChR , Antifungal
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b...
T6602 Naratriptan hydrochloride Naratriptan HCl,Amerge,Naramig,GR-85548A hydrochloride 5-HT Receptor
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydroc...
T21423 Methysergide maleate Deseril, Sansert,UML 491,UML491,Methysergide,UML-491
Methysergide is used for prophylaxis of migraine headaches/cluster headaches but is no longer recommended due to retropulmonary/retroperitoneal fibrosis. It may also be used in the treatment of serotonin syndrome. It is ...
T26079 RI 61 RI-61,Pro-his-pro-phe-his-leu-phe-val-phe,RI61
RI 61 (sumatriptan succinate) is utilized in the therapy of migraine, cluster headaches, new daily persistent headache, and cyclic vomiting syndrome.
T70257 Avitriptan HCl
Avitriptan, also known as BMS-180048, is a selective 5-HT1-like receptor agonist. Avitriptan is an effective compound for the treatment of migraine headaches with a prolonged duration of response. Avitriptan Is a Ligan...
T71800 Metoprolol HCl
Metoprolol is a selective β1 receptor blocker medication. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. It is...
T79806 5-HT2A&5-HT2C agonist-1 5-HT Receptor
5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM. It is applicable in the study of various central nervous system disor...
T79804 5-HT2 agonist-1 5-HT Receptor
Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. The free base form of this compound is utilized in research pertaini...

Compounds

Valproic acid sodium salt
T1602
Synonym: Sodium Valproate
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, HDAC, Autophagy
Valproic Acid
T7064
Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy
Divalproex Sodium
T6474
Synonym: Valproate semisodium,Epival
Target: HDAC
Etilefrine pivalate HCl
T68067L
Synonym: Etilefrine pivalate HCl(100696-30-8 Free base)
Target:
Stacofylline
T68145
Synonym:
Target:
Galcanezumab
T76682
Synonym: LY 2951742
Target: CGRP Receptor
Naratriptan
T8666
Synonym:
Target: 5-HT Receptor
Zolmitriptan
T1092
Synonym: 311C90,BW-311C90
Target: 5-HT Receptor
Rizatriptan benzoate
T1512
Synonym: MK-462 Benzoate
Target: 5-HT Receptor
Betahistine mesylate
T0246L
Synonym: Extovyl,Melopat,Meginalisk
Target: Histamine Receptor
Betahistine
T4195
Synonym: PT 9 base,Vasomotal,Serc base
Target: Histamine Receptor
Propoxur
T0976
Synonym: Aprocarb,Propoxure,Baygon
Target: AChR, Antifungal
Naratriptan hydrochloride
T6602
Synonym: Naratriptan HCl,Amerge,Naramig,GR-85548A hydrochloride
Target: 5-HT Receptor
Methysergide maleate
T21423
Synonym: Deseril, Sansert,UML 491,UML491,Methysergide,UML-491
Target:
RI 61
T26079
Synonym: RI-61,Pro-his-pro-phe-his-leu-phe-val-phe,RI61
Target:
Avitriptan HCl
T70257
Synonym:
Target:
Metoprolol HCl
T71800
Synonym:
Target:
5-HT2A&5-HT2C agonist-1
T79806
Synonym:
Target: 5-HT Receptor
5-HT2 agonist-1
T79804
Synonym:
Target: 5-HT Receptor
TargetMol