19
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1602 | Valproic acid sodium salt | Sodium Valproate | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy |
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha... | |||
T7064 | Valproic Acid | Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy |
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research. | |||
T6474 | Divalproex Sodium | Valproate semisodium,Epival | HDAC |
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme... | |||
T68067L | Etilefrine pivalate HCl | Etilefrine pivalate HCl(100696-30-8 Free base) | |
Etilefrine pivalate HCl is an orally active compound for the treatment of migraine headaches. | |||
T68145 | Stacofylline | ||
Stacofylline is a xanthine derivative that is used to treat migraine headaches. | |||
T76682 | Galcanezumab | LY 2951742 | CGRP Receptor |
Galcanezumab is a humanized IgG4 monoclonal antibody targeting the CGRP ligand, which binds to the ligand calcitonin gene-related peptide. Galcanezumab can be used to prevent and treat migraines or cluster headaches. | |||
T8666 | Naratriptan | 5-HT Receptor | |
Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches. | |||
T1092 | Zolmitriptan | 311C90,BW-311C90 | 5-HT Receptor |
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and... | |||
T1512 | Rizatriptan benzoate | MK-462 Benzoate | 5-HT Receptor |
Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches. | |||
T0246L | Betahistine mesylate | Extovyl,Melopat,Meginalisk | Histamine Receptor |
Betahistine mesylate (Extovyl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. | |||
T4195 | Betahistine | PT 9 base,Vasomotal,Serc base | Histamine Receptor |
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti... | |||
T0976 | Propoxur | Aprocarb,Propoxure,Baygon | AChR , Antifungal |
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b... | |||
T6602 | Naratriptan hydrochloride | Naratriptan HCl,Amerge,Naramig,GR-85548A hydrochloride | 5-HT Receptor |
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydroc... | |||
T21423 | Methysergide maleate | Deseril, Sansert,UML 491,UML491,Methysergide,UML-491 | |
Methysergide is used for prophylaxis of migraine headaches/cluster headaches but is no longer recommended due to retropulmonary/retroperitoneal fibrosis. It may also be used in the treatment of serotonin syndrome. It is ... | |||
T26079 | RI 61 | RI-61,Pro-his-pro-phe-his-leu-phe-val-phe,RI61 | |
RI 61 (sumatriptan succinate) is utilized in the therapy of migraine, cluster headaches, new daily persistent headache, and cyclic vomiting syndrome. | |||
T70257 | Avitriptan HCl | ||
Avitriptan, also known as BMS-180048, is a selective 5-HT1-like receptor agonist. Avitriptan is an effective compound for the treatment of migraine headaches with a prolonged duration of response. Avitriptan Is a Ligan... | |||
T71800 | Metoprolol HCl | ||
Metoprolol is a selective β1 receptor blocker medication. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. It is... | |||
T79806 | 5-HT2A&5-HT2C agonist-1 | 5-HT Receptor | |
5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM. It is applicable in the study of various central nervous system disor... | |||
T79804 | 5-HT2 agonist-1 | 5-HT Receptor | |
Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. The free base form of this compound is utilized in research pertaini... |