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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T29000 | Tralomethrin | EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout | |
Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron... | |||
T71755 | QNN33358 | ||
QNN33358 is an alkylacylglycerol acts as a protein kinase C (PKC) inhibitor and diacylglycerol (DAG) antagonist. | |||
T9181 | Autophagy-IN-A9 | Others | |
Autophagy-IN-A9 is a bioactive chemical. | |||
T13809 | P62-mediated mitophagy inducer | PMI | Mitophagy |
P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy . | |||
T8946 | Indophagolin | P2X Receptor , 5-HT Receptor , Autophagy | |
Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively. | |||
T62331 | Autophagy-IN-1 | ||
Autophagy-IN-1 is a potent inhibitor of autophagy/mitophagy, blocking autophagosomal-lysosomal fusion in cancer cells while selectively increasing autophagic flux. Autophagy-IN-1 significantly inhibits tumour growth in t... | |||
T124201 | Chagreslactone | ||
Chagreslactone is a useful organic compound for research related to life sciences. The catalog number is T124201 and the CAS number is 799269-22-0. | |||
T38977 | Autophagy-IN-C1 | Autophagy-IN-C1 | |
Autophagy-IN-C1 is a cinchona alkaloid derivative containing urea. Autophagy-IN-C1 not only induces apoptosis but also blocks autophagy in hepatocellular carcinoma (HCC) cells. | |||
T61580 | Autophagy inducer 3 | ||
Autophagy Inducer 3 is a chemical compound that exhibits autophagy-induced activity, specifically inducing robust autophagic cell death in various cancer cells while sparing normal cells. This compound induces lethal aut... | |||
T63744 | Autophagy inducer 4 | ||
Autophagy inducer 4 is a Mannich base derivative based on Magnolol and can be used as an anticancer agent. autophagy inducer 4 induces autophagy and thus inhibits cancer cells. autophagy inducer 4 is 76 times more toxic ... | |||
T60749 | Autophagy-IN-2 | ||
Autophagy-IN-2 (Compound 7h) is an inhibitor of autophagic flux which induces cancer cell apoptosis and can be used for the research of triple-negative breast cancer [1]. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN4179 | Haginin A | ERK , Tyrosinase , Akt | |
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activation, MITF, and also by the subsequent downregulation of t... | |||
TN3429 | Aphagranin A | Others | |
Aphagranin A exhibits strong antiproliferative activity against the growth of six lines of human cancer cells (MCF-7, A549, HepG2, Bel-7402, SGC-7901, and BGC-823. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00698 | AGR2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progressi... | |||
TMPJ-00789 | Flagellin Protein, Salmonella Typhimurium, Recombinant | Salmonella typhimurium | E. coli |
Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin... | |||
TMPY-04205 | AGR3 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associat... | |||
TMPJ-00050 | AG-3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metasta... | |||
TMPJ-00056 | AG-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcin... | |||
TMPY-06572 | Vaccinia virus (VACV) (strain Copenhagen) Protein B5 (His) | VACV | HEK293 Cells |
Vaccinia virus (VACV) (strain Copenhagen) Protein B5 (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.53 kDa and the accession number is P21115. | |||
TMPY-04960 | Der p 1 Protein, Dermatophagoides pteronyssinus, Recombinant (His) | Dermatophagoides pteronyssinus | HEK293 Cells |
Der p 1 Protein, Dermatophagoides pteronyssinus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.7 kDa and the accession number is P08176. | |||
TMPY-04945 | Der p 2 Protein, Dermatophagoides pteronyssinus, Recombinant (His) | Dermatophagoides pteronyssinus | E. coli |
Hypersensitivity to house dust mite (Dermatophagoides sp.) allergens is one of the most common allergic reactions in the world. The house dust mite allergen, Der p 2, is a major allergen and 80–90% of patients who react ... | |||
TMPY-02288 | Glyoxalase II/HAGH Protein, Human, Recombinant (His) | Human | E. coli |
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase an... | |||
TMPH-00474 | Der p 6 Protein, Dermatophagoides pteronyssinus, Recombinant (GST) | Dermatophagoides pteronyssinus | E. coli |
Der p 6 Protein, Dermatophagoides pteronyssinus, Recombinant (GST) is expressed in E. coli. | |||
TMPH-00525 | DsDNA-binding protein A Protein, Enterobacteria phage T4, Recombinant (His & Myc) | Enterobacteria phage T4 | E. coli |
May play a role in transcription of several T4 genes. Binds double-stranded DNA and interacts preferentially with T4 late promoter regions. DsDNA-binding protein A Protein, Enterobacteria phage T4, Recombinant (His & Myc... | |||
TMPH-03665 | Vaccinia virus (strain Copenhagen) OPG185 Protein (His) | VACV | E. coli |
Prevents cell to cell fusion by interacting with and directing the viral K2 protein on the host plasma membrane. The A56-K2 complex associates with components of the entry fusion complex (EFC) presumably to avoid superin... | |||
TMPY-06975 | Der p 21 Protein, Dermatophagoides pteronyssinus, Recombinant | Dermatophagoides pteronyssinus | E. coli |
Der p 21 Protein, Dermatophagoides pteronyssinus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.55 kDa. | |||
TMPH-00526 | Endolysin Protein, Enterobacteria phage T4, Recombinant (His & SUMO) | Enterobacteria phage T4 | E. coli |
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral part... | |||
TMPH-03643 | TmpB Protein, Treponema phagedenis, Recombinant (His & Myc) | Treponema phagedenis | E. coli |
Tmp may serve as a porin or transport protein for large molecules. TmpB Protein, Treponema phagedenis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecula... | |||
TMPY-06573 | Vaccinia virus (VACV) (strain Copenhagen) L1R Protein (His) | VACV | HEK293 Cells |
Vaccinia virus (VACV) (strain Copenhagen) L1R Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.59 kDa and the accession number is P20540. | |||
TMPH-00517 | StxB2 Protein, Enterobacteria phage 933W, Recombinant (His) | Enterobacteria phage 933W | P. pastoris (Yeast) |
The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli. | |||
TMPH-00053 | 50S ribosomal protein L22, Anaplasma phagocytophilum, Recombinant (His & Myc) | Anaplasma phagocytophilum | E. coli |
50S ribosomal protein L22, Anaplasma phagocytophilum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.2 kDa and the accession number is ... | |||
TMPH-00756 | Capsid Protein, Escherichia phage MS2, Recombinant (His & Myc) | Escherichia phage MS2 | E. coli |
Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 26 nm in diameter, and consisting of 89 capsid proteins dimers (178 capsid proteins). Involved in viral genome encapsidation through ... | |||
TMPH-00520 | Host-nuclease inhibitor protein gam Protein, Enterobacteria phage lambda, Recombinant (His & Myc) | Escherichia phage lambda | E. coli |
Binds to host RecBCD nuclease and inhibits it thereby protecting the viral DNA against recBCD mediated degradation. | |||
TMPH-03673 | Vaccinia virus (strain Copenhagen) L1 Protein (His & Myc) | VACV | Baculovirus Insect Cells |
Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion ... | |||
TMPY-06575 | Vaccinia virus (VACV) (strain Copenhagen) A27L Protein (His) | VACV | E. coli |
Vaccinia virus (VACV) (strain Copenhagen) A27L Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.46 kDa and the accession number is P20535. | |||
TMPH-00528 | Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His) | Enterobacteria phage T4 | E. coli |
Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins. | |||
TMPH-00755 | Integrase Protein, Escherichia phage lambda, Recombinant (His) | Escherichia phage lambda | E. coli |
Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Int... | |||
TMPH-00524 | ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) | Enterobacteria phage T4 | E. coli |
DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule be... | |||
TMPH-00472 | Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His & Myc) | Dermatophagoides pteronyssinus | E. coli |
Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00754 | Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) | Escherichia phage lambda | E. coli |
Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while ... | |||
TMPY-05078 | Der f 2 Protein, Dermatophagoides farinae, Recombinant (His) | Dermatophagoides farinae | E. coli |
Der f 2 Protein, Dermatophagoides farinae, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15 kDa and the accession number is Q00855.1. | |||
TMPY-05518 | Der p 5 Protein, Dermatophagoides pteronyssinus, Recombinant (His) | Dermatophagoides pteronyssinus | E. coli |
Der p 5 Protein, Dermatophagoides pteronyssinus, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.6 kDa and the accession number is A0A6P6Y2A6. | |||
TMPH-03658 | Vaccinia virus (strain Copenhagen) Ag35 Protein (His & Myc) | VACV | E. coli |
Envelope protein that binds to heparan sulfate on the cell surface and might provide virion attachment to target cell. Vaccinia virus (strain Copenhagen) Ag35 Protein (His & Myc) is expressed in E. coli expression system... | |||
TMPH-00531 | SSB Protein, Enterobacteria phage T7, Recombinant (His & SUMO) | Enterobacteria phage T7 | E. coli |
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance... | |||
TMPH-03651 | Tyr p 2 Protein, Tyrophagus putrescentiae, Recombinant (His) | Tyrophagus putrescentiae | E. coli |
N/A. Tyr p 2 Protein, Tyrophagus putrescentiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.3 kDa and the accession number is O02380. | |||
TMPH-03663 | Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, His) | VACV | Baculovirus Insect Cells |
Coordinates the incorporation of A36 into intracellular enveloped virion (IEV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral parti... | |||
TMPH-00516 | StxA2 Protein, Enterobacteria phage 933W, Recombinant (E189K, His & Myc) | Enterobacteria phage 933W | E. coli |
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the cata... | |||
TMPY-05710 | Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His) | Dermatophagoides pteronyssinus | HEK293 Cells |
Der p 23 is a new major allergen of D. pteronyssinus. The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma. Der p 23 may be an essenti... | |||
TMPH-03667 | Vaccinia virus (strain Copenhagen) OPG190 Protein (His) | VACV | P. pastoris (Yeast) |
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EEV) to allow virion entry into host cells. Participates also in wrapping intracellular mature virions (IMV) to form intracell... | |||
TMPH-03655 | Vaccinia virus (strain Copenhagen) OPG105 Protein (His & SUMO) | VACV | E. coli |
Binds to chondroitin sulfate on the cell surface to provide virion attachment to target cell. Vaccinia virus (strain Copenhagen) OPG105 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag... | |||
TMPH-00529 | UvsY Protein, Enterobacteria phage T4, Recombinant (Avi & His) | Enterobacteria phage T4 | E. coli |
Plays a role in viral DNA synthesis by promoting enzymatic activities of UvsX recombinase, by promoting UvsX-ssDNA filament assembly, and by helping UvsX to displace bound gp32 from ssDNA. | |||
TMPH-00522 | Recombinase cre Protein, Enterobacteria phage P1, Recombinant (His & Myc) | Escherichia phage P1 | E. coli |
Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state. | |||
TMPH-03666 | Vaccinia virus (strain Copenhagen) OPG190 Protein (His & Myc) | VACV | E. coli |
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EEV) to allow virion entry into host cells. Participates also in wrapping intracellular mature virions (IMV) to form intracell... | |||
TMPH-00473 | Der p 3 Protein, Dermatophagoides pteronyssinus, Recombinant (His) | Dermatophagoides pteronyssinus | E. coli |
Der p 3 Protein, Dermatophagoides pteronyssinus, Recombinant (His) is expressed in E. coli. | |||
TMPY-05140 | Der f 1 Protein, Dermatophagoides farinae, Recombinant (His) | Dermatophagoides farinae | HEK293 Cells |
Der f 1 Protein, Dermatophagoides farinae, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and the accession number is Q58A71. | |||
TMPH-03674 | Vaccinia virus (strain Copenhagen) L1 Protein (E. coli, His & Myc) | VACV | E. coli |
Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion ... | |||
TMPH-03662 | Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, E. coli, His) | VACV | E. coli |
Coordinates the incorporation of A36 into intracellular enveloped virion (IEV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral parti... | |||
TMPH-03656 | Vaccinia virus (strain Copenhagen) TopIB Protein (His) | VACV | E. coli |
Vaccinia virus (strain Copenhagen) TopIB Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.7 kDa and the accession number is P68697. | |||
TMPH-03678 | Vaccinia virus (strain Copenhagen) OPG125 Protein (His & Myc) | VACV | E. coli |
Vaccinia virus (strain Copenhagen) OPG125 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.2 kDa and the accession number is P68441. | |||
TMPH-00521 | G3P Protein, Enterobacteria phage M13, Recombinant (His) | Enterobacteria phage M13 | P. pastoris (Yeast) |
Plays essential roles both in the penetration of the viral genome into the bacterial host via pilus retraction and in the extrusion process. During the initial step of infection, G3P mediates adsorption of the phage to i... | |||
TMPH-03677 | Vaccinia virus (strain Copenhagen) OPG065 Protein (His & Myc) | VACV | E. coli |
Vaccinia virus (strain Copenhagen) OPG065 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.5 kDa and the accession number is P21081. | |||
TMPY-06574 | Vaccinia virus (VACV) (strain Copenhagen) A33R Protein (His) | VACV | E. coli |
Vaccinia virus (VACV) (strain Copenhagen) A33R Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.18 kDa and the accession number is P68616. | |||
TMPY-05139 | Der p 10 Protein, Dermatophagoides pteronyssinus, Recombinant | Dermatophagoides pteronyssinus | E. coli |
Der p 10 Protein, Dermatophagoides pteronyssinus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 32.9 kDa and the accession number is O18416.1. | |||
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Cat No. | Product Name | ||
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L3200 | Autophagy Compound Library | 1248 compounds | |
A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs; |