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TargetMol | Compound Library

Autophagy Compound Library

Catalog No. L3200

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1470 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3200

Autophagy Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1470 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Autophagy
Apoptosis
PI3K
mTOR
Akt
Antibacterial
Endogenous Metabolite
AMPK
GSK-3
Antibiotic
NF-κB
p38 MAPK
Mitophagy
CDK
Parasite
ROS
HIV Protease
ERK
Reactive Oxygen Species
CXCR
HDAC
DNA-PK
Ferroptosis
S6 Kinase
DNA/RNA Synthesis
Raf
VEGFR
ATM/ATR
Potassium Channel
MEK
PKC
Cytochromes P450
COX
Caspase
Ras
Src
Bcr-Abl
PDK
Virus Protease
PPAR
Retinoid Receptor
Adrenergic Receptor
EGFR
SARS-CoV
LRRK2
Calcium Channel
PDGFR
Bcl-2 Family
TNF
JNK
PKA
Wnt/beta-catenin
Nrf2
STAT
FLT
c-Kit
Interleukin
Influenza Virus
Dehydrogenase
Antifungal
Topoisomerase
Aurora Kinase
MMP
Casein Kinase
FGFR
AChR
CFTR
CaMK
PI4K
5-HT Receptor
Estrogen/progestogen Receptor
HMG-CoA Reductase
PARP
FXR
JAK
FAAH
Microtubule Associated
PDE
HSV
TLR
HIF/HIF Prolyl-Hydroxylase
ATPase
PERK
ROCK
Mitochondrial Metabolism
IGF-1R
c-Myc
ATG
TRP/TRPV Channel
IL Receptor
TGF-beta/Smad
MAPK
HSP
Proteasome
Dopamine Receptor
PTEN
p53
c-Met/HGFR
Phosphatase
Estrogen Receptor/ERR
Nucleoside Antimetabolite/Analog
Glucocorticoid Receptor
SIK
Chk
Lipoxygenase
P-gp
Sirtuin
ALK
IκB/IKK
Beta Amyloid
c-RET
MDM-2/p53
Proton pump
Antioxidant
Serine/threonin kinase
Epigenetic Reader Domain
GABA Receptor
HIF
Sodium Channel
FAK
NO Synthase
Adenosine Receptor
DYRK
NADPH
Histamine Receptor
Rho
Trk receptor
MELK
Phospholipase
SGK
ROS Kinase
Histone Methyltransferase
HCV Protease
Integrin
Progesterone Receptor
MRP
Tyrosine Kinases
Cysteine Protease
Glucokinase
Gamma-secretase
Glucosidase
Antifection
Opioid Receptor
Hedgehog/Smoothened
glycosidase
DUB
Prostaglandin Receptor
transporter
Reverse Transcriptase
Cannabinoid Receptor
Anti-infection
NOS
Carbonic Anhydrase
Transferase
DHFR
ADC Cytotoxin
DNA Alkylator/Crosslinker
RAAS
Tie-2
Pim
Serotonin Transporter
MAO
RIP kinase
LDL
Drug Metabolite
Fatty Acid Synthase
GluR
Androgen Receptor
FKBP
c-Fms
ribosome
PLK
DNA Methyltransferase
PD-1/PD-L1
Dynamin
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
Reductase
Glutathione Peroxidase
GTPase
HBV
Antifolate
Aryl Hydrocarbon Receptor
P2X Receptor
ABC Transporter
Monoamine Transporter
DPP-4
Cholinesterase (ChE)
Cadherin
DNA
Survivin
MNK
GST
p62
CRISPR/Cas9
Syk
NOD
Tyrosinase
NOD-like Receptor (NLR)
Kinesin
S1P Receptor
Monoamine Oxidase
GPCR
Mdm2
NPC1L1
RAR/RXR
ROR
MyD88
YAP
BACE
Arrestin
Cell wall
IDO
IAP
iGluR
IRE1
Myosin
E1/E2/E3 Enzyme
UGT
NMDAR
DNA Alkylation
CCR
Angiotensin-converting Enzyme (ACE)
Norepinephrine
Indoleamine 2,3-Dioxygenase (IDO)
ATP Citrate Lyase
Lipid
OXPHOS
Beta-Secretase
Antiviral
Histone Acetyltransferase
FOXO
Complement System
REV-ERB
ATTECs
BMI-1
Lysosomal Autophagy
AhR
MLK
HER
Apelin receptor
Chloride channel
Adenylyl Cyclase
Y Box Binding Protein 1
Arginase
LPL Receptor
Na+/Ca2+ Exchanger
Lipase
Necroptosis
gp120/CD4
TOPK
VDA
Melatonin Receptor
Cholecystokinin Receptor
Photosensitizer
Serine Protease
NAMPT
PYK2
Glutaminase
RANKL/RANK
Immunology/Inflammation related
CSF-1R
Prolyl Endopeptidase (PREP)
Annexin A
PAFR
GRK
DNA gyrase
Na-K-Cl cotransporter
Hexokinase
Molecular Glues
Guanylate cyclase
Smo
MAGL
Vasopressin Receptor
ACK1
Endothelin Receptor
Somatostatin
cAMP
BCRP
Acyltransferase
STING
Aminopeptidase
GPCR19
Ephrin Receptor
Decarboxylase
ASK
GluCls
Pyroptosis
Acetyl-CoA Carboxylase
KRas
Ligand for E3 Ligase
Aromatase
Gap Junction Protein
DAPK
IRAK
Sigma receptor
Thrombin
p97
Imidazoline Receptor
BTK
PGC-1α

Keywords