Home Tools
Log in
Products Inhibitors Libraries Recombinant Proteins Kits Services Contact Us
Cart
Peptides Monoclonal Antibodies Dye Reagents PROTAC Virtual Screening TargetMol Kits Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails Natural Products Phenols Alkaloids Flavonoids
Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Autophagy Compound Library

Catalog No. L3200
  Library Compound List   Excel SDF

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1248 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
Request Library
Get quote

Product Description

  • A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L3200)

Publications Cited TargetMol Libraries

1. Cells. 2023, 12(12): 1642. 2. Cell Stem Cell. 2022 Apr 29(4) 545–558. 3. Science Bulletin. 2022. 4. Science Translational Medicine. 2022, 14(656): eabn3231. 5. Science Advances. 2023, 9(9): eade3760. 6. Nature. 2020, 582: 289-293. 7. Nature Biotechnology. 2021, 39(11): 1444-1452. 8. Nature Communications. 2022, 13(1): 1-15.. 9. Nature Communications. 2023, 14(1): 1020..
Hide

Library Composition

Autophagy (824)
Apoptosis (333)
PI3K (99)
Antibacterial (92)
mTOR (72)
Endogenous Metabolite (67)
Antibiotic (65)
Mitophagy (54)
AMPK (46)
p38 MAPK (41)
HIV Protease (40)
Ferroptosis (39)
NF-κB (39)
HDAC (39)
Akt (39)
Parasite (34)
Reactive Oxygen Species (34)
CXCR (31)
Raf (30)
Calcium Channel (27)
Potassium Channel (27)
VEGFR (26)
Adrenergic Receptor (24)
Aurora Kinase (23)
CDK (23)
COX (23)
Retinoid Receptor (23)
MEK (22)
p53 (22)
ERK (22)
EGFR (22)
DNA-PK (22)
DNA/RNA Synthesis (21)
Influenza Virus (20)
FLT (20)
c-Kit (20)
P450 (20)
Bcr-Abl (20)
PDGFR (19)
Topoisomerase (17)
PKC (17)
Src (17)
5-HT Receptor (17)
AChR (17)
LRRK2 (17)
CFTR (16)
Antifungal (16)
Virus Protease (16)
GSK-3 (16)
CaMK (15)
SARS-CoV (15)
PKA (15)
BCL (14)
FGFR (14)
Proteasome (14)
JNK (14)
E1/E2/E3 Enzyme (13)
HMG-CoA Reductase (13)
FXR (13)
FAAH (13)
TNF (13)
S6 Kinase (13)
JAK (12)
STAT (12)
Microtubule Associated (12)
Sirtuin (12)
Ras (12)
Sodium Channel (12)
HSV (11)
HIF/HIF Prolyl-Hydroxylase (11)
PDE (11)
PPAR (11)
MMP (11)
Estrogen/progestogen Receptor (11)
Dopamine Receptor (11)
Serine/threonin kinase (10)
Nrf2 (10)
ATM/ATR (10)
PERK (10)
TLR (10)
DUB (10)
Epigenetic Reader Domain (10)
c-RET (10)
Caspase (10)
TGF-beta/Smad (9)
Dehydrogenase (9)
Casein Kinase (9)
Mitochondrial Metabolism (9)
Mdm2 (9)
Antioxidant (8)
ROCK (8)
Phosphatase (8)
TRP/TRPV Channel (8)
HIF (8)
Nucleoside Antimetabolite/Analog (8)
PARP (8)
HSP (7)
ATPase (7)
Proton pump (7)
Histamine Receptor (7)
c-Met/HGFR (7)
Histone Methyltransferase (7)
Glucocorticoid Receptor (7)
IκB/IKK (7)
Trk receptor (7)
PTEN (6)
Beta Amyloid (6)
c-Myc (6)
Estrogen Receptor/ERR (6)
Tyrosine Kinases (6)
IL Receptor (6)
Lipoxygenase (6)
P-gp (6)
MAO (6)
IGF-1R (6)
GABA Receptor (6)
ALK (6)
ribosome (5)
Phospholipase (5)
PDK (5)
ROS (5)
HER (5)
Cysteine Protease (5)
Rho (5)
Wnt/beta-catenin (5)
NADPH (5)
Hedgehog/Smoothened (4)
Progesterone Receptor (4)
Gamma-secretase (4)
DNA Methyltransferase (4)
Serine Protease (4)
Aryl Hydrocarbon Receptor (4)
NOS (4)
Serotonin Transporter (4)
DNA Alkylator/Crosslinker (4)
MRP (4)
GluR (4)
DHFR (4)
Carbonic Anhydrase (4)
HCV Protease (4)
Integrin (4)
Reverse Transcriptase (4)
transporter (4)
Prostaglandin Receptor (4)
c-Fms (4)
IAP (4)
FAK (4)
Opioid Receptor (4)
ROS Kinase (4)
DPP-4 (4)
Glucokinase (4)
PLK (3)
RAAS (3)
Amino Acids and Derivatives (3)
Androgen Receptor (3)
Pim (3)
Ligand for E3 Ligase (3)
SIK (3)
Antifolate (3)
Dynamin (3)
Adenosine Receptor (3)
DNA (3)
P2X Receptor (3)
SGK (3)
Monoamine Oxidase (3)
HBV (3)
Fatty Acid Synthase (3)
ABC (3)
Molecular Glues (3)
Transferase (3)
Cannabinoid Receptor (3)
NO Synthase (3)
RIP kinase (3)
S1P Receptor (2)
lysosomal autophagy (2)
GTPase (2)
VDA (2)
NOD-like Receptor (NLR) (2)
AhR (2)
MLK (2)
ROR (2)
p97 (2)
Glutathione Peroxidase (2)
CRISPR/Cas9 (2)
Tyrosinase (2)
TAM Receptor (2)
BMI-1 (2)
NOD (2)
Syk (2)
ATTECs (2)
NMDAR (2)
GPR (2)
Histone Acetyltransferase (2)
Ligands for Target Protein for PROTAC (2)
MNK (2)
Chk (2)
CCR (2)
BACE (2)
PGC-1α (2)
LDL (2)
Norepinephrine (2)
IRE1 (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
Cell wall (2)
Interleukin (2)
DNA Alkylation (2)
MAPK (2)
AChE (2)
iGluR (2)
DYRK (2)
YAP (2)
Antifection (2)
BTK (2)
Antiviral (2)
Drug Metabolite (2)
Reductase (1)
Anti-infection (1)
DNA gyrase (1)
Glucosidase (1)
PAFR (1)
Kinesin (1)
PD-1/PD-L1 (1)
IRAK (1)
Imidazoline Receptor (1)
Melatonin Receptor (1)
Smo (1)
Guanylate cyclase (1)
Tie-2 (1)
RAR/RXR  (1)
Sigma receptor (1)
IFNAR (1)
Hexokinase (1)
Na+/Ca2+ Exchanger (1)
Thrombin (1)
Endothelin Receptor (1)
Arrestin (1)
Monoamine Transporter (1)
GRK (1)
PROTAC Linker (1)
Factor Xa (1)
Adenylyl cyclase (1)
ACK (1)
CAT (1)
PAI-1 (1)
Liver X Receptor (1)
Leukotriene Receptor (1)
Survivin (1)
NAMPT (1)
Glutaminase (1)
Lipase (1)
GluCls (1)
Beta-Secretase (1)
IDO (1)
STING (1)
Ephrin Receptor (1)
FOXO1 (1)
GPCR19 (1)
Aminopeptidase (1)
MyD88 (1)
Arginase (1)
Gap Junction Protein (1)
Myosin (1)
UGT (1)
Somatostatin (1)
Complement System (1)
Histone Demethylase (1)
NPC1L1 (1)
Annexin A (1)
TOPK (1)
PI4K (1)
LPL Receptor (1)
Lipid (1)
ATP Citrate Lyase (1)
OXPHOS (1)
BCRP (1)
CSF-1R (1)
LTR (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
CORPORATE
About Us Careers Privacy Notice Events & News Terms & Conditions
SUPPORT
Contact Us Worldwide Distributors Quality Control Technical Support
RESOURCE
Product Catalog Product Citations Signaling Pathways Solution Calculators
FOLLOW OUR
Social Network
Newsletter Subscription
Subscribe to receive our lastest product updates and special offers!
Corporate
Support
Resource
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
TargetMol
Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved.