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TargetMol | Compound Library

Autophagy Compound Library

Catalog No. L3200

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1470 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3200

Autophagy Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1470 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Autophagy
Apoptosis
PI3K
mTOR
Akt
Antibacterial
Endogenous Metabolite
AMPK
GSK-3
Antibiotic
Mitophagy
p38 MAPK
CDK
Parasite
NF-κB
HIV Protease
HDAC
Reactive Oxygen Species
CXCR
ERK
DNA-PK
Ferroptosis
S6 Kinase
Raf
VEGFR
ATM/ATR
Potassium Channel
DNA/RNA Synthesis
PKC
Cytochromes P450
MEK
COX
Ras
PDK
Retinoid Receptor
Src
LRRK2
Bcr-Abl
Adrenergic Receptor
Virus Protease
Calcium Channel
EGFR
PDGFR
Caspase
c-Kit
JNK
PKA
SARS-CoV
Influenza Virus
FLT
PPAR
Bcl-2 Family
Topoisomerase
Dehydrogenase
TNF
FGFR
STAT
Wnt/beta-catenin
Casein Kinase
CFTR
AChR
Aurora Kinase
5-HT Receptor
Antifungal
PI4K
FXR
Nrf2
Estrogen/progestogen Receptor
HMG-CoA Reductase
MMP
Microtubule Associated
CaMK
FAAH
PDE
TLR
ROCK
ATPase
PERK
HSV
JAK
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
PARP
TRP/TRPV Channel
TGF-beta/Smad
IL Receptor
MAPK
PTEN
p53
Dopamine Receptor
ATG
IGF-1R
Proteasome
Interleukin
HSP
Phosphatase
Glucocorticoid Receptor
Nucleoside Antimetabolite/Analog
Sirtuin
Estrogen Receptor/ERR
SIK
IκB/IKK
c-RET
Chk
c-Met/HGFR
c-Myc
Lipoxygenase
ALK
MDM-2/p53
Sodium Channel
Proton pump
Antioxidant
Epigenetic Reader Domain
GABA Receptor
HIF
Serine/threonin kinase
P-gp
FAK
NADPH
Beta Amyloid
SGK
Histamine Receptor
Phospholipase
Trk receptor
Rho
MELK
ROS Kinase
HCV Protease
Cysteine Protease
Opioid Receptor
Prostaglandin Receptor
Cannabinoid Receptor
NO Synthase
Histone Methyltransferase
MRP
Antifection
transporter
Anti-infection
Tyrosine Kinases
Integrin
Glucosidase
Glucokinase
Gamma-secretase
ROS
DUB
Adenosine Receptor
DYRK
Reverse Transcriptase
NOS
DNA Alkylator/Crosslinker
LDL
FKBP
RIP kinase
Drug Metabolite
Androgen Receptor
Transferase
ADC Cytotoxin
Pim
DNA Methyltransferase
Carbonic Anhydrase
GluR
ribosome
DHFR
RAAS
Tie-2
Serotonin Transporter
Hedgehog/Smoothened
c-Fms
Progesterone Receptor
MAO
Glutathione Peroxidase
Aryl Hydrocarbon Receptor
Tyrosinase
Antifolate
P2X Receptor
Fatty Acid Synthase
NOD-like Receptor (NLR)
Monoamine Oxidase
HBV
ABC Transporter
Cholinesterase (ChE)
DNA
p62
CRISPR/Cas9
Dynamin
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
DPP-4
MNK
PLK
Syk
S1P Receptor
GTPase
GST
NOD
PD-1/PD-L1
RAR/RXR
MyD88
Arrestin
IRE1
Cadherin
Norepinephrine
OXPHOS
ATTECs
MLK
UGT
Indoleamine 2,3-Dioxygenase (IDO)
Kinesin
YAP
BACE
Cell wall
IDO
Lipid
Antiviral
BMI-1
AhR
IAP
iGluR
E1/E2/E3 Enzyme
Monoamine Transporter
CCR
ATP Citrate Lyase
HER
NPC1L1
Reductase
Myosin
DNA Alkylation
Beta-Secretase
FOXO
ROR
NMDAR
Angiotensin-converting Enzyme (ACE)
Complement System
GPCR
Mdm2
Histone Acetyltransferase
REV-ERB
Lysosomal Autophagy
Chloride channel
Melatonin Receptor
Prolyl Endopeptidase (PREP)
DNA gyrase
Guanylate cyclase
MAGL
GluCls
Pyroptosis
Adenylyl Cyclase
LPL Receptor
PYK2
Glutaminase
Somatostatin
BCRP
Survivin
Aminopeptidase
DAPK
p97
Necroptosis
RANKL/RANK
Annexin A
GRK
Na-K-Cl cotransporter
Molecular Glues
ACK1
Thrombin
VDA
KRas
Sigma receptor
Imidazoline Receptor
TOPK
Cholecystokinin Receptor
CSF-1R
Smo
Endothelin Receptor
Acyltransferase
Decarboxylase
Ligand for E3 Ligase
Apelin receptor
Lipase
Serine Protease
Immunology/Inflammation related
PAFR
Hexokinase
GPCR19
Y Box Binding Protein 1
Arginase
Na+/Ca2+ Exchanger
gp120/CD4
Photosensitizer
NAMPT
Vasopressin Receptor
cAMP
Ephrin Receptor
Aromatase
Gap Junction Protein
IRAK
PGC-1α
BTK

Keywords