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TargetMol | Compound Library

Autophagy Compound Library

Catalog No. L3200

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1470 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3200

Autophagy Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1470 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Autophagy
Apoptosis
PI3K
mTOR
Akt
Antibacterial
Endogenous Metabolite
AMPK
GSK-3
NF-κB
Antibiotic
p38 MAPK
Mitophagy
CDK
Parasite
ROS
HIV Protease
ERK
Reactive Oxygen Species
HDAC
CXCR
DNA-PK
Ferroptosis
S6 Kinase
Raf
ATM/ATR
VEGFR
DNA/RNA Synthesis
Potassium Channel
MEK
Ras
PKC
Cytochromes P450
Caspase
Bcr-Abl
Src
Adrenergic Receptor
COX
Virus Protease
Retinoid Receptor
PPAR
PDK
EGFR
Calcium Channel
SARS-CoV
LRRK2
TNF
JNK
PDGFR
Influenza Virus
Bcl-2 Family
PKA
Wnt/beta-catenin
Nrf2
STAT
FLT
c-Kit
Interleukin
Aurora Kinase
AChR
Topoisomerase
Dehydrogenase
FGFR
Casein Kinase
CFTR
Antifungal
MMP
CaMK
PI4K
5-HT Receptor
Estrogen/progestogen Receptor
JAK
FXR
HMG-CoA Reductase
Microtubule Associated
FAAH
PARP
HSV
PDE
TLR
HIF/HIF Prolyl-Hydroxylase
ATPase
IGF-1R
Mitochondrial Metabolism
ROCK
Dopamine Receptor
c-Myc
TGF-beta/Smad
HSP
PERK
ATG
IL Receptor
MAPK
TRP/TRPV Channel
PTEN
P-gp
Beta Amyloid
c-Met/HGFR
ALK
MDM-2/p53
Sodium Channel
Estrogen Receptor/ERR
SIK
IκB/IKK
c-RET
Nucleoside Antimetabolite/Analog
Phosphatase
p53
Chk
Glucocorticoid Receptor
FAK
Rho
Lipoxygenase
GABA Receptor
HIF
Proteasome
Epigenetic Reader Domain
Antioxidant
Sirtuin
Proton pump
Serine/threonin kinase
Adenosine Receptor
DYRK
MELK
ROS Kinase
Histamine Receptor
Phospholipase
HCV Protease
NO Synthase
Trk receptor
SGK
Histone Methyltransferase
MRP
Antifection
Progesterone Receptor
Integrin
Glucosidase
Hedgehog/Smoothened
Tyrosine Kinases
glycosidase
Cysteine Protease
Opioid Receptor
Cannabinoid Receptor
Glucokinase
Gamma-secretase
DUB
NADPH
Anti-infection
RIP kinase
Drug Metabolite
Fatty Acid Synthase
Androgen Receptor
MAO
Reverse Transcriptase
NOD
PD-1/PD-L1
DHFR
RAAS
Tie-2
Serotonin Transporter
Carbonic Anhydrase
GluR
ribosome
NOS
Prostaglandin Receptor
FKBP
c-Fms
PLK
Transferase
ADC Cytotoxin
Pim
transporter
DNA Methyltransferase
Antifolate
P2X Receptor
Survivin
Kinesin
GTPase
GST
Reductase
HBV
ABC Transporter
Monoamine Transporter
Cholinesterase (ChE)
DNA
p62
CRISPR/Cas9
DNA Alkylator/Crosslinker
Glutathione Peroxidase
Aryl Hydrocarbon Receptor
LDL
Cadherin
Tyrosinase
Dynamin
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
DPP-4
MNK
Syk
S1P Receptor
NOD-like Receptor (NLR)
Monoamine Oxidase
PGC-1α
Adenylate cyclase
UGT
Indoleamine 2,3-Dioxygenase (IDO)
GPCR
Mdm2
BTK
Histone Acetyltransferase
REV-ERB
Lysosomal Autophagy
NPC1L1
Myosin
DNA Alkylation
Beta-Secretase
FOXO
IAP
iGluR
E1/E2/E3 Enzyme
CCR
ATP Citrate Lyase
HER
RAR/RXR
MyD88
Arrestin
IRE1
Norepinephrine
OXPHOS
MLK
ROR
NMDAR
Angiotensin-converting Enzyme (ACE)
PANoptosis
Complement System
YAP
BACE
IDO
Lipid
BMI-1
AhR
LPL Receptor
PYK2
Glutaminase
Ligands for E3 Ligase
Somatostatin
BCRP
Aminopeptidase
ASK
DAPK
p97
Y Box Binding Protein 1
Arginase
Na+/Ca2+ Exchanger
gp120/CD4
Photosensitizer
NAMPT
Vasopressin Receptor
cAMP
Ephrin Receptor
Aromatase
Gap Junction Protein
IRAK
TOPK
Cholecystokinin Receptor
CSF-1R
Smo
Endothelin Receptor
Acyltransferase
Decarboxylase
VDA
KRas
Sigma receptor
Imidazoline Receptor
Chloride channel
Melatonin Receptor
Prolyl Endopeptidase (PREP)
DNA gyrase
Guanylate cyclase
MAGL
STING
GluCls
Pyroptosis
Acetyl-CoA Carboxylase
ATTECs
Apelin receptor
Lipase
Serine Protease
Immunology/Inflammation related
PAFR
Hexokinase
GPCR19
Cell wall
Necroptosis
RANKL/RANK
Annexin A
GRK
Na-K-Cl cotransporter
Molecular Glues
ACK1
Antiviral
Thrombin

Keywords