genotoxic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19137	4'-Methylacetophenone		Others
	4'-Methylacetophenone can be used as a fragrance material. It is wildly occurred in volatile compounds in food and in some natural complex substances.		Others
T38003	Levofloxacin N-oxide		Others
	Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin . Levofloxacin N-oxide is also a degradation product of levofloxacin that is formed through exposure to daylight or hydrogen peroxide.		Others
T10148	4-Hydroxynonenal	4-HNE	Dehydrogenase , Endogenous Metabolite
	4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).		Dehydrogenase , Endogenous Metabolite
T19081	1,3-Dithiane	1,3-Dithian,M-DITHIANE,1,3-Dithiacyclohexane	Anti-infection , Endogenous Metabolite , Antibacterial
	1,3-Dithiane (1,3-Dithian) is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon. 1,3-Dithiane is also a sulfur-containing Maillard reaction products found in boiled beef extracts.		Anti-infection , Endogenous Metabolite , Antibacterial
T31532	Disperse Red 1	Celliton Scarlet B,Neosetile Scarlet B,Diacelliton Scarlet B,Fenacet Scarlet B,Celliton Red B	Others
	Disperse Red 1 (Celliton Scarlet B) is an azo dye that contributes to the toxicity and pollution of wastewater.		Others
TN1886	Lucidin primeveroside	Lucidin 3-O-primeveroside	Topoisomerase
	Lucidin primeveroside (Lucidin 3-O-primeveroside) is a natural product isolated from the root powder of akane (Rubia akane) and can be used as a coloring agent and a food pigment. Lucidin primeveroside can be metabolical...		Topoisomerase
T22309	2,5-Dimethyl-3(2H)-furanone	2,5-Dimethyl-2,3-dihydrofuran-3-one	Others
	2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) is a non-genotoxic flavoring substance [1].		Others
T22857	Illudin S		Apoptosis , DNA Alkylator/Crosslinker , Antifungal
	Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.		Apoptosis , DNA Alkylator/Crosslinker , Antifungal
TJS0405	Lucidin	NSC 30546,Henine	Others
	1. Lucidin (NSC-30546) and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.		Others
T37101	1-Hydroxyanthraquinone		DNA/RNA Synthesis
	1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.		DNA/RNA Synthesis
T2204	Diaveridine	EGIS-5645,CCRIS-3784,AI3-23935	DHFR , Antifolate , Antibacterial
	Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cells, but more studies are required to clarify th...		DHFR , Antifolate , Antibacterial
TN2258	Tartrazine	FD&C Yellow No. 5,Acid Yellow 23	Others
	Tartrazine (Acid Yellow 23) is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carc...		Others
T1887	Inauhzin	INZ	Sirtuin
	Inauhzin (INZ)(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A54...		Sirtuin
T19051	Reactive Blue 4		Others
	Reactive Blue 4 is an anthraquinone dye with phytotoxic, cytotoxic, and genotoxic. It is a single colorimetric chemosensor for the sequential determination of multiple analytes with different optical responses in aqueous...		Others
TN2245	Sunset Yellow FCF	Food Yellow 3,Orange Yellow S,Sunset yellow,CI 15985	Androgen Receptor
	Sunset Yellow FCF (Sunset yellow) is an orange azo dye with pH-dependent absorbance.Sunset Yellow FCF is used in food, cosmetics and pharmaceuticals.It is used as a colorant food additive in many food products.They may b...		Androgen Receptor
T40740	Dibromochloroacetaldehyde
	Dibromochloroacetaldehyde, a trihalogenated acetaldehyde compound, is present as a byproduct in drinking water. It exhibits genotoxic properties.
T28117	MSN-50	MSN50,MSN 50
	MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.
T41127	Bromochloroacetaldehyde
	Bromochloroacetaldehyde is a dihalogenated acetaldehyde compound that is commonly found as a byproduct in drinking water. It exhibits genotoxic properties.
T69845	MX107
	MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.
T69840	MX106
	MX106 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.