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Diaveridine

Catalog No. T2204 CAS 5355-16-8

Synonyms: 敌菌净, 二氨藜芦啶, EGIS-5645, CCRIS-3784, AI3-23935

Diaveridine (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cells, but more studies are required to clarify this.

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Diaveridine, CAS 5355-16-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Diaveridine (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cells, but more studies are required to clarify this.
Targets&IC50	dihydrofolate reductase (DHFR):11.5 nM (ki)

Synonyms	敌菌净, 二氨藜芦啶, EGIS-5645, CCRIS-3784, AI3-23935
Molecular Weight	260.297
Formula	C13H16N4O2
CAS No.	5355-16-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 23 mg/mL(88.4 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Ono T, et al. Environ Toxicol Pharmacol. 1997 Sep;3(4):297-306.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Anti-Cancer Metabolism Compound Library Antibiotics Library DNA Damage & Repair Compound Library Immunology/Inflammation Compound Library Anti-Metabolism Disease Compound Library Cell Cycle Compound Library FDA-Approved & Pharmacopeia Drug Library Anti-Bacterial Compound Library Anti-Aging Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Diaveridine 5355-16-8 DNA损伤和修复代谢微生物学细胞周期 Antibacterial Antifolate DHFR CCRIS-3784 EGIS5645 EGIS-5645 Bacterial AI3-23935 Inhibitor EGIS 5645 inhibit inhibitor

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