fms — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10643	C-Fms-IN-1		c-Fms
	c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).		c-Fms
T10775	C-Fms-IN-2		c-Fms
	c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).		c-Fms
T10649	C-Fms-IN-3		c-Fms
	c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.		c-Fms
T61589	C-Fms-IN-13		c-Fms
	c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.		c-Fms
T10648	C-Fms-IN-9		c-Fms
	c-Fms-IN-9 is a c-FMS inhibitor. It inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT (IC50s: <0.01 μM and 0.1-1 μM).		c-Fms
T10646	C-Fms-IN-7		Others
	c-Fms-IN-7 is a cFMS inhibitor (IC50: 18.5 nM).		Others
T10645	C-Fms-IN-6		c-Fms
	c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).		c-Fms
T10647	C-Fms-IN-8		CSF-1R
	c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.		CSF-1R
T10644	C-Fms-IN-10		Others
	c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity.		Others
T64050	C-Fms-IN-12
	c-Fms-IN-12 is an FMS kinase inhibitor that also inhibits c-KIT and induces apoptosis in A549 cells. c-Fms-IN-12 is a potential broad-spectrum anti-cancer agent that has demonstrated therapeutic effects in a variety of c...
T79815	C-Fms-IN-14		c-Fms
	c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].		c-Fms
T27345	FMS586	FMS-586,FMS 586
	FMS586 is a selective antagonist of neuropeptide Y Y5 receptor with oral activity.
T2620	G-749	G749	Apoptosis , FLT , c-RET , TAM Receptor , Aurora Kinase
	G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.		Apoptosis , FLT , c-RET , TAM Receptor , Aurora Kinase
T5586	CFMS Receptor Inhibitor II		c-Fms
	cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor		c-Fms
T2340	AC1NS4RE		Tyrosinase
	It is a tyrosine kinase inhibitor.		Tyrosinase
T4209	TAK-659 hydrochloride	TAK-659	VEGFR , FLT , Tyrosine Kinases , JAK , Syk
	TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.		VEGFR , FLT , Tyrosine Kinases , JAK , Syk
T1938	FLT3-IN-2		FLT
	FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).		FLT
T4428	CCT241736		FLT , Aurora Kinase
	CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3, CCT241736, an advanced analog of CCT137690, is a preclinica...		FLT , Aurora Kinase
T10894	CSF1R-IN-1		c-Fms
	CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.		c-Fms
T2272	BPR1J-097	BPR1J097	FLT
	BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM).		FLT