Powder: -20°C for 3 years | In solvent: -80°C for 2 years
CCT241736 is an orally bioavailable dual FLT3/Aurora Kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3, CCT241736, an advanced analog of CCT137690, is a preclinical development candidate for the treatment of human malignancies, and in particular AML in adults and children.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 55.00 | |
10 mg | In stock | $ 89.00 | |
25 mg | In stock | $ 179.00 | |
50 mg | In stock | $ 347.00 | |
100 mg | In stock | $ 519.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 61.00 |
Description | CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3, CCT241736, an advanced analog of CCT137690, is a preclinical development candidate for the treatment of human malignancies, and in particular AML in adults and children. |
Targets&IC50 | FLT3:, Aurora Kinase: |
In vivo | UNC2025 was capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow. |
Molecular Weight | 456.37 |
Formula | C22H23Cl2N7 |
CAS No. | 1402709-93-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
DMSO: 75 mg/mL (164.34 mM), Need ultrasonic
H2O: < 0.1 mg/mL (insoluble)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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CCT241736 1402709-93-6 Angiogenesis Cell Cycle/Checkpoint Chromatin/Epigenetic Tyrosine Kinase/Adaptors FLT Aurora Kinase CCT 241736 Fms like tyrosine kinase 3 CD135 Inhibitor FLT3 CCT-241736 Cluster of differentiation antigen 135 inhibit inhibitor