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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8485 | THIQ | Melanocortin Receptor | |
THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively). | |||
TN2088 | Platycodin D2 | IL Receptor , HBV | |
Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalaci... | |||
T0824 | 4-Nonylphenol polyethoxylate | Nonoxynol,Nonoxinol-9 | COX |
4-Nonylphenol polyethoxylate (Nonoxinol-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/... | |||
T2163 | Dihydrocapsaicin | CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide | Others , TRP/TRPV Channel |
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an... | |||
T15502 | HQ-415 | Others | |
HQ-415 is a class of clinically relevant bioactive metal chelators related to clioquinol. The effective concentration eliciting an EC50 for HQ-415 is 15 μM. | |||
T40511 | TET 830 modified/T-helper epitope from tetanus toxoid | ||
TET 830 modified/T-helper epitope from tetanus toxoid is a T-cell stimulating peptide derived from tetanus toxoid. It acts as a helper peptide in vaccinations, eliciting T-cell responses. | |||
T14035 | 3M-011 | TLR | |
3M-011, a potent dual toll-like receptor TLR7/8 agonist and cytokine inducer, serves as a powerful adjuvant to radiotherapy, eliciting significant local and systemic immune responses. Additionally, it effectively inhibit... | |||
T37617 | Leukotriene B3 | ||
LTB3 is the LTA hydrolase metabolite of LTA3 in the leukotriene biosynthetic pathway. LTB3 and LTB4 are equipotent in their pro-inflammatory effects. However, LTB3 is five times less potent than LTB4 in eliciting chemota... | |||
T37668 | CAY10448 | CAY10448 | |
Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or... | |||
T81502 | Pezadeftide | Antibiotic | |
Pezadeftide, a potent antifungal peptide, readily penetrates fungal cells, eliciting an immediate mitochondrial response that leads to hyperpolarization of the mitochondrial membrane [1]. | |||
T78000 | OVA Peptide (323-339) | ||
OVA Peptide (323-339) constitutes a T and B cell epitope derived from Ovalbumin (Ova), crucial for eliciting immediate hypersensitivity reactions in BALB/c mice. | |||
T36238 | 6α-Prostaglandin I1 | 6α-Prostaglandin I1 | |
6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration depende... | |||
T82280 | Gly-Gly-Arg | ||
Gly-Gly-Arg, a tripeptide and "pumping pheromone," is released from hatching eggs, stimulating pleopod pumping activity in subtidal crustaceans at a threshold concentration of 10 nM and eliciting a maximum response rate ... | |||
T81444 | PL-3994 | ||
PL-3994, a natriuretic peptide receptor-A (NPR-A) agonist resistant to neutral endopeptidase, functions as a bronchodilator, eliciting a concentration-dependent relaxation of pre-contracted guinea-pig trachea, evidenced ... | |||
T78809 | NDNA3 | HSP | |
NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10A cells, with IC50 values of 12.66 μM and 11.72 μM respectively. ... | |||
T78808 | NDNA4 | HSP | |
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability. It exhibits minimal cytotoxicity against Ovcar-8 and MCF-10A cell lines (IC50 >100... | |||
T78006 | Prolactin Releasing Peptide (1-31), human acetate | ||
Prolactin Releasing Peptide (1-31), human (acetate), is a potent GPR10 ligand with high affinity, eliciting prolactin secretion. It binds to human and rat GPR10 with K_i values of 1.03 nM and 0.33 nM, respectively, and s... | |||
T83406 | 2,3-Diphospho-D-glyceric acid pentasodium salt | 2,3-DPG pentasodium salt | |
2,3-Diphospho-D-glyceric acid pentasodium salt is a highly anionic polyphosphorus compound located within the concave center of red blood cells, where it decreases oxygen affinity by binding to hemoglobin. This endogenou... | |||
T35598 | Neuromedin U-25 (human) (trifluoroacetate salt) | ||
Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction.1Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-med... |