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Search Results for " eliciting "

19

Compounds

Cat No. Product Name Synonyms Targets
T8485 THIQ Melanocortin Receptor
THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).
TN2088 Platycodin D2 IL Receptor , HBV
Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalaci...
T0824 4-Nonylphenol polyethoxylate Nonoxynol,Nonoxinol-9 COX
4-Nonylphenol polyethoxylate (Nonoxinol-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/...
T2163 Dihydrocapsaicin CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide Others , TRP/TRPV Channel
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...
T15502 HQ-415 Others
HQ-415 is a class of clinically relevant bioactive metal chelators related to clioquinol. The effective concentration eliciting an EC50 for HQ-415 is 15 μM.
T40511 TET 830 modified/T-helper epitope from tetanus toxoid
TET 830 modified/T-helper epitope from tetanus toxoid is a T-cell stimulating peptide derived from tetanus toxoid. It acts as a helper peptide in vaccinations, eliciting T-cell responses.
T14035 3M-011 TLR
3M-011, a potent dual toll-like receptor TLR7/8 agonist and cytokine inducer, serves as a powerful adjuvant to radiotherapy, eliciting significant local and systemic immune responses. Additionally, it effectively inhibit...
T37617 Leukotriene B3
LTB3 is the LTA hydrolase metabolite of LTA3 in the leukotriene biosynthetic pathway. LTB3 and LTB4 are equipotent in their pro-inflammatory effects. However, LTB3 is five times less potent than LTB4 in eliciting chemota...
T37668 CAY10448 CAY10448
Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or...
T81502 Pezadeftide Antibiotic
Pezadeftide, a potent antifungal peptide, readily penetrates fungal cells, eliciting an immediate mitochondrial response that leads to hyperpolarization of the mitochondrial membrane [1].
T78000 OVA Peptide (323-339)
OVA Peptide (323-339) constitutes a T and B cell epitope derived from Ovalbumin (Ova), crucial for eliciting immediate hypersensitivity reactions in BALB/c mice.
T36238 6α-Prostaglandin I1 6α-Prostaglandin I1
6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration depende...
T82280 Gly-Gly-Arg
Gly-Gly-Arg, a tripeptide and "pumping pheromone," is released from hatching eggs, stimulating pleopod pumping activity in subtidal crustaceans at a threshold concentration of 10 nM and eliciting a maximum response rate ...
T81444 PL-3994
PL-3994, a natriuretic peptide receptor-A (NPR-A) agonist resistant to neutral endopeptidase, functions as a bronchodilator, eliciting a concentration-dependent relaxation of pre-contracted guinea-pig trachea, evidenced ...
T78809 NDNA3 HSP
NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10A cells, with IC50 values of 12.66 μM and 11.72 μM respectively. ...
T78808 NDNA4 HSP
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability. It exhibits minimal cytotoxicity against Ovcar-8 and MCF-10A cell lines (IC50 >100...
T78006 Prolactin Releasing Peptide (1-31), human acetate
Prolactin Releasing Peptide (1-31), human (acetate), is a potent GPR10 ligand with high affinity, eliciting prolactin secretion. It binds to human and rat GPR10 with K_i values of 1.03 nM and 0.33 nM, respectively, and s...
T83406 2,3-Diphospho-D-glyceric acid pentasodium salt 2,3-DPG pentasodium salt
2,3-Diphospho-D-glyceric acid pentasodium salt is a highly anionic polyphosphorus compound located within the concave center of red blood cells, where it decreases oxygen affinity by binding to hemoglobin. This endogenou...
T35598 Neuromedin U-25 (human) (trifluoroacetate salt)
Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction.1Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-med...
TargetMol