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Platycodin D2

Catalog No. TN2088 CAS 66663-90-9

Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Platycodin D2, CAS 66663-90-9

Pack Size	Availability	Price/USD	Quantity
20 mg	In stock	$ 330.00
1 mL * 10 mM (in DMSO)	In stock	$ 350.00

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Purity: 98.83%

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Description	Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses.
Targets&IC50	proliferation:4 - 18 microg/mL(ED50)
In vitro	A novel triterpenoid saponin, deapioplatycoside E (1) was isolated from the root extract of Platycodon grandiflorum, together with the seven known saponins 2 - 8, i. e., platycoside E (2), deapioplatycodin D3 (3), platycodin D3 (4), polygalacin D2 (5), Platycodin D2 (6), deapioplatycodin D (7) and platycodin D (8). The structure of the new saponin 1 was determined on the basis of spectral analysis and chemical evidence[1]

Molecular Weight	1387.46
Formula	C63H102O33
CAS No.	66663-90-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 100 mg/mL (72.07 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Kim YS, et al. Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines. Planta Med. 2005 Jun;71(6):566-8. 2. Xie Y, et al. Platycodin D2 improves specific cellular and humoral responses to hepatitis B surface antigen in mice. Chem Biodivers. 2010 Jan;7(1):178-85.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Inflammatory Traditional Chinese Medicine Compound Library Traditional Mongolian Medicine Compound Library Anti-Tumor Natural Product Library Bioactive Compound Library Selected Plant-Sourced Compound Library Anti-Cancer Compound Library Natural Product Library for HTS Anti-virus Traditional Chinese Medicine Monomer Library Traditional Chinese Medicine Monomer Library Natural Product Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Platycodin D2 66663-90-9 Microbiology/Virology Immunology/Inflammation IL Receptor HBV inhibit Platycodin D 2 Inhibitor Platycodin D-2 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.