deficiency — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12499	PKR-IN-2		PKM
	PKR-IN-2 is a activator of pyruvate kinase (PKR).		PKM
T41160	Lalistat 2		Lipase
	Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM).		Lipase
T4223	Mitapivat	PKR-IN-1	PKM
	Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.		PKM
T4505	Ferrous Bisglycinate	Bisglycine iron(II) salt,Iron(II) bisglycinate	Estrogen/progestogen Receptor
	Ferrous Bisglycinate (Bisglycine iron(II) salt) is used in the fortification of infant formulations and foods.		Estrogen/progestogen Receptor
T0613	3-Hydroxyisovaleric acid	Beta-Hydroxyisovaleric acid	Others , Endogenous Metabolite
	3-Hydroxyisovaleric acid (Beta-Hydroxyisovaleric acid) is an endogenous metabolite excreted in the urine and can serve as an early and sensitive indicator of biotin deficiency.		Others , Endogenous Metabolite
T29856	Aleplasinin	PAZ 417,PAZ417,PAZ-417	PAI-1
	Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies...		PAI-1
T1536	Promestriene	3-propyl ethyl,17B-methyl estradiol,Promestriano	Estrogen/progestogen Receptor
	Promestriene (3-propyl ethyl) (INN) is a synthetic estrogen and glucocorticoid used topically in a 1% cream formulation. It is described as a tropic agent and antiseborrheic.		Estrogen/progestogen Receptor
T0062	Folic acid	Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin	DNA/RNA Synthesis , Endogenous Metabolite
	Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis.		DNA/RNA Synthesis , Endogenous Metabolite
T13692	Ferric maltol	Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate	Others
	Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) is a ferric, non-salt-based oral iron formulation demonstrating improved tolerance in patients with previous intolerance to other iron formulations.		Others
T13396	Zinc Protoporphyrin	Zinc Protoporphyrin-9,ZnPP,Zn(II)-protoporphyrin IX	Apoptosis , Reactive Oxygen Species , Endogenous Metabolite
	Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-can...		Apoptosis , Reactive Oxygen Species , Endogenous Metabolite
T7313	Enclomiphene citrate	Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate	Estrogen Receptor/ERR
	Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property		Estrogen Receptor/ERR
T3S0507	Homovanillic acid	Homovaniuic acid,Vanilacetic acid,Vanillacetic acid	Others , Endogenous Metabolite
	Homovanillic acid (Vanillacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, growth hormone deficiency, celiac disease, and sepiapterin reductase deficiency.		Others , Endogenous Metabolite
T4851	Methyl acetylacetate	Methyl acetoacetate	Others , Endogenous Metabolite
	Methyl acetylacetate (Methyl acetoacetate) has been identified in the urine of patients with an inherited deficiency of propionyl-CoA carboxylase, and after isoleucine loading in the diagnosis of 2-methylacetoacetyl-CoA ...		Others , Endogenous Metabolite
T4734	Suberic acid	Octanedioic acid,1,8-Octanedioic acid	Others , Endogenous Metabolite
	Suberic acid (1,8-Octanedioic acid) is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dicarboxylic acid ar...		Others , Endogenous Metabolite
T5273	2-Hydroxy-3-methylbutanoic acid	2-Hydroxy-3-methylbutyric acid,2-Hydroxyisovaleric Acid,(±)-2-Hydroxyisopentanoic Acid	Others , Endogenous Metabolite
	2-Hydroxy-3-methylbutanoic acid ((±)-2-Hydroxyisopentanoic Acid) is a metabolite found in the urine of patients with phenylketonuria, methylmalonic acidemia, propionic acidemia, 3-ketothiolase deficiency, isovaleric acid...		Others , Endogenous Metabolite
T19581	Tiglyl carnitine		Endogenous Metabolite
	Tiglyl carnitine is associated with lung cancer and carnitine and glycine to 3-ketothiolase deficiency .		Endogenous Metabolite
T3036	Dydrogesterone		Progesterone Receptor
	Dydrogesterone is a potent progestogen which can be used in progesterone deficiency studies.		Progesterone Receptor
T5279	Ethylmalonic acid	alpha-Carboxybutyrate,2-Ethylmalonic acid	Others , Endogenous Metabolite
	Ethylmalonic acid (alpha-Carboxybutyrate) can be found in blood, cerebrospinal fluid (CSF), and urine, as well as in human fibroblasts, prostate, and skeletal muscle tissues. Moreover, ethylmalonic acid is found to be as...		Others , Endogenous Metabolite
TQ0024	3-Hydroxyglutaric acid		Endogenous Metabolite
	3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available. It is used as a biomarker of GCDH deficiency.		Endogenous Metabolite
T8132	Iron sucrose	Iron saccharate,Sucroferric oxyhydroxide	Reactive Oxygen Species
	Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.		Reactive Oxygen Species