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3-Hydroxyglutaric acid

Name: 3-Hydroxyglutaric acid
Brand: TargetMol
SKU: TQ0024
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TQ0024Cas No. 638-18-6

3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available. It is used as a biomarker of GCDH deficiency.

3-Hydroxyglutaric acid

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Purity: 99.93%

Catalog No. TQ0024Cas No. 638-18-6

3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available. It is used as a biomarker of GCDH deficiency.

Pack Size	Price	Availability
5 mg	$39	In Stock
10 mg	$64	In Stock
25 mg	$122	In Stock
50 mg	$178	In Stock
100 mg	$268	In Stock
200 mg	$398	In Stock

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Batch Information

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Purity:99.93%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available. It is used as a biomarker of GCDH deficiency.

Chemical Properties

Molecular Weight	148.11
Formula	C₅H₈O₅
Cas No.	638-18-6
Smiles	OC(CC(O)=O)CC(O)=O
Relative Density.	1.508g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 30 mg/mL (202.55 mM), Sonication is recommended.

DMSO: 50 mg/mL (337.59 mM), Sonication is recommended.

Ethanol: 30 mg/mL (202.55 mM), Sonication is recommended.

Solution Preparation Table

DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	6.7517 mL	33.7587 mL	67.5174 mL	337.5869 mL
5 mM	1.3503 mL	6.7517 mL	13.5035 mL	67.5174 mL
10 mM	0.6752 mL	3.3759 mL	6.7517 mL	33.7587 mL
20 mM	0.3376 mL	1.6879 mL	3.3759 mL	16.8793 mL
50 mM	0.1350 mL	0.6752 mL	1.3503 mL	6.7517 mL
100 mM	0.0675 mL	0.3376 mL	0.6752 mL	3.3759 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc