Home Tools
Log in
Cart

Iron sucrose

Catalog No. T8132   CAS 8047-67-4
Synonyms: Iron saccharate, Sucroferric oxyhydroxide

Iron sucrose is treatment of iron deficiency anemia.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Iron sucrose, CAS 8047-67-4
Pack Size Availability Price/USD Quantity
100 mg In stock $ 41.00
200 mg In stock $ 58.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
Bulk Inquiry
Get quote
Select Batch  
Purity: N/A
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description Iron sucrose is treatment of iron deficiency anemia.
In vitro In vitro conditions iron induces a dose-dependent inhibition of viability of the mesothelial cells as reflected by inhibition of the cells growth by 34% at Fe 0.1 mg mL-1 vs. control (P <?0.05) increased release of lactate dehydrogenase (LDH) from the cytosol: 67.1 +/- 30.3 mU mL-1 at Fe 1 mg mL-1 vs. 7.9 +/- 6.4 in control group (P <?0.001), and reduced synthesis of IL-6: 209 +/- 378 pg mg-1 cell protein at Fe 1 mg mL-1 vs. 38674 +/- 4146 pg mg-1 cell protein in controls (P <?0.001).?Cytotoxicity of iron towards mesothelial cells was enhanced in vitro when it was tested in presence of the dialysis fluid.?Iron used in vitro at concentration 0.0001 mg mL-1 and greater induces generation of oxygen-derived free radicals in mesothelial cells.?Furthermore, iron is taken by these cells and stored in their cytosol, resulting in stimulation of the intracellular generation of free radicals[1].
Cell Research in vitro experiments on human peritoneal, the mesothelial effect of elemental iron (in conc. 0.0001-1 mg mL-1) present in Venofer on their viability, growth and synthesis of IL-6 was studied. Additionally we evaluated with a fluorescent probe (2',7'-dichlorodihydro-fluorescein diacatate) generation of reactive oxygen species in cells exposed to iron sucrose. We also measured accumulation of iron in the cytoplasm of mesothelial cells after their in vitro exposure to Venofer[1].
Synonyms Iron saccharate, Sucroferric oxyhydroxide
Molecular Weight 736.1
Formula C18H24Fe2O24
CAS No. 8047-67-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 100 mg/mL (135.85 mM)

H2O: 100 mg/mL (135.85 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Breborowicz M , Polubinska A , Tam P , et al. Effect of iron sucrose on human peritoneal mesothelial cells[J]. European Journal of Clinical Investigation, 2003, 33(12):1038-1044. 2. Kaneva K , Chow E , Rosenfield C G , et al. Intravenous Iron Sucrose for Children With Iron Deficiency Anemia[J]. Journal of Pediatric Hematology/oncology, 2017:1.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Prostate Cancer Compound Library Anti-Breast Cancer Compound Library Approved Drug Library Pyroptosis Compound Library Immunology/Inflammation Compound Library Anti-Cancer Approved Drug Library Anti-Liver Cancer Compound Library Anti-Cancer Compound Library Anti-Cardiovascular Disease Compound Library NF-κB Signaling Compound Library

Related Products

Related compounds with same targets
NM-3 Antroquinonol Pelargonidin chloride Isotrifoliin Epiberberine chloride Uric acid sodium 5-Hydroxyoxindole Rutaevin

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Dosage
mg/kg
Average weight of animals
g
Dosing volume per animal
ul
Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
Calculate Reset

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator
=
X
X

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

X
=
X

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

=
/

Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Iron sucrose 8047-67-4 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species H2O2 pregnancy ascorbate IDA Intravenous ICAM-1 inhibit NADPH Iron saccharate NF-κB Sucroferric oxyhydroxide Inhibitor VCAM-1 hemoglobin anemia iron safe inhibitor