cgmp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14064	8-Bromo-cGMP sodium		Calcium Channel , PKA
	8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhibits Ca2+ macroscopic currents, and inhibits high K+-stimula...		Calcium Channel , PKA
T68374	8-Nitro-cGMP
	8-Nitro-cGMP is a unique cytoprotective mediator which inhibits oxidative stress. 8-Nitro-cGMP is also a probe of the protein S-guanylation.
T11038	Dibutyryl-cGMP sodium	Bt2cGMP sodium	Others
	Dibutyryl-cGMP sodium (Bt2cGMP sodium) is a cell-permeable cGMP analog. Dibutyryl-cGMP sodium preferentially activates cGMP-dependent protein kinase (PKG). Dibutyryl-cGMP sodium inhibits [3H]-arachidonic acid release in ...		Others
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD	Monosodium-GMP,cGMP sodium salt,Cyclic GMP	PKA
	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc...		PKA
T74018	cGMP-HTL
	cGMP-HTL, an autophagy-targeting chimera (AUTAC), consists of a HT-ligand, a linker, and a Cys-S-cGMP (autophagy tag), designed to enhance K63-linked ubiquitination of mitochondria. This novel clearance strategy features...
T82632	Cys-C-cGMP		AUTACs
	Cys-C-cGMP serves as an autophagy tag for AUTACs (autophagy-targeting chimeras). It enhances K63-linked ubiquitination of mitochondria within HeLa cells [1].		AUTACs
T83402	2′,3′-cGMP triethylamine	Guanosine 2',3'-cyclic phosphate triethylamine
	Guanosine 2',3'-cyclic phosphate triethylamine, commonly known as 2′,3′-cGMP triethylamine, is an active compound utilizable in numerous research investigations [1].
TP1903	PKG inhibitor peptide	cGMP Dependent Kinase Inhibitor Peptide
	Competitive inhibitor of cGMP-dependent protein kinase (PKG); analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (Ki = 86 mM) but does not inhibit pho...
T21965	MBCQ		PDE
	MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.		PDE
T21607	Ataciguat	HMR-1766	Others , Guanylate cyclase
	Ataciguat (HMR-1766) (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.		Others , Guanylate cyclase
T13189	TP-10		PDE
	TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.		PDE
T0096	Vardenafil	Vivanza,Levitra,Vardenafil hydrochloride	PDE
	Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemod...		PDE
T8405	Vardenafil hydrochloride		PDE
	Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes		PDE
T4097	Vardenafil hydrochloride trihydrate	Vardenafil HCl Trihydrate,BAY38-9456	PDE
	Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.		PDE
T6888	Methylene Blue	methylthioninium chloride,CI-52015,Tetramethylthionine chloride,Basic Blue 9	Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase
	Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy.
T0006	Methylene Blue trihydrate	Methylthionine chloride,Basic blue 9,Methylene Blue	Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase
	Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate...
T4480	Vardenafil dihydrochloride	Levitra,Vardenafil Hydrochloride	PDE
	Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.		PDE
T23252	Rp-8-Br-PET-cGMPS		Others
	cGMP-dependent protein kinase (PKG) inhibitor		Others
T7321	MBP146-78		Parasite
	MBP146-78 is a potent and selective cGMP inhibitor dependent protein kinases.		Parasite
T1398	Tadalafil	Cialis,IC-351	Apoptosis , PDE
	Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGM...		Apoptosis , PDE