Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 42.00 | |
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 409.00 | |
100 mg | In stock | $ 590.00 | |
500 mg | In stock | $ 1,270.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 75.00 |
Description | MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5. |
Targets&IC50 | PDE1:>100 μM (IC50), PDE3:>100 μM (IC50), PDE2:>100 μM (IC50), PDE5:19 nM (IC50), PDE4:>100 μM (IC50) |
In vitro | MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins[1]. |
Molecular Weight | 313.74 |
Formula | C16H12ClN3O2 |
CAS No. | 150450-53-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (79.68 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MBCQ 150450-53-6 Metabolism PDE cGMP-PDE inhibit arteries PGF2α Inhibitor Phosphodiesterase (PDE) coronary inhibitor