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Search Results for " bile "

20

Compounds

Cat No. Product Name Synonyms Targets
T2934 Bilirubin Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin Endogenous Metabolite
Bilirubin (Principal bile pigment) is a principal pigment of bile and one of the major end products of hemoglobin decomposition.
T5077 Deoxycholic acid sodium salt Sodium deoxycholate,Sodium Desoxycholate Endogenous Metabolite , GPCR19
Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
T19189 Allocholic acid Others
Allocholic acid is a fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis. It is also a potent and specific stimulant of the adult olfactory system.
T8153 Glycohyodeoxycholic acid Others , Endogenous Metabolite
glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans.
T2965 Deoxycholic acid Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic Endogenous Metabolite , GPCR19
Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorptio...
T0700 Ursodeoxycholic acid UDCA,Ursodiol Potassium Channel , Endogenous Metabolite
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
T1285 Anethole trithione Anetholtrithion Others , AChR
Anethole trithione (Anetholtrithion) is a bile secretion-stimulating drug that restores salivation and relieves the discomfort of dry mouth in chemotherapy-induced xerostomia.
T7428 SBI-115 GPCR19
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T0022 Taurine 2-Aminoethanesulfonic acid LDL , Endogenous Metabolite , Autophagy
Taurine (2-Aminoethanesulfonic acid), an organic acid, is distributed in various animal tissues.
T4083 BAR501 BAR 501 GPCR19
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
TQ0252 BAR502 FXR , GPCR19 , Autophagy
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
T4352 SB756050 SB-756050,SB 756050 GPCR19
SB756050 is a specific TGR5 agonist.
T8599 Betazole dihydrochloride Betazole hydrochloride Histamine Receptor
Betazole dihydrochloride (Betazole hydrochloride) is an agonist of H2 receptor.
T11515 Gut restricted-7 GR-7 Potassium Channel
Gut restricted-7 (GR-7) (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. It decreases gut bacterial BSHs and decreases deconjugated bile acid levels in the feces of mice.
T29078 Ursodeoxycholic acid sodium UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium FXR , Endogenous Metabolite , GPCR19
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...
T31964 Glycolithocholic acid Lithocholic acid glycine conjugate,Lithocholylglycine Others
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.
T2A2481 Taurochenodeoxycholic Acid Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine Apoptosis , TNF , Caspase , Endogenous Metabolite
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
T1824 TGR5 Receptor Agonist GPCR19
TGR5 is a potent TGR5(GPCR19) agonist.
T13502 3-Oxo-5β-cholanoic acid Dehydrolithocholic acid ROR
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd: 1.13 μM)...
T2968 Hyodeoxycholic acid NSC 60672,α-Hyodeoxycholic Acid,HDCA FXR , Endogenous Metabolite , GPCR19
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.

Compounds

Bilirubin
T2934
Synonym: Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin
Target: Endogenous Metabolite
Deoxycholic acid sodium salt
T5077
Synonym: Sodium deoxycholate,Sodium Desoxycholate
Target: Endogenous Metabolite, GPCR19
Allocholic acid
T19189
Synonym:
Target: Others
glycohyodeoxycholic acid
T8153
Synonym:
Target: Others, Endogenous Metabolite
Deoxycholic acid
T2965
Synonym: Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic
Target: Endogenous Metabolite, GPCR19
Ursodeoxycholic acid
T0700
Synonym: UDCA,Ursodiol
Target: Potassium Channel, Endogenous Metabolite
Anethole trithione
T1285
Synonym: Anetholtrithion
Target: Others, AChR
SBI-115
T7428
Synonym:
Target: GPCR19
Taurine
T0022
Synonym: 2-Aminoethanesulfonic acid
Target: LDL, Endogenous Metabolite, Autophagy
BAR501
T4083
Synonym: BAR 501
Target: GPCR19
BAR502
TQ0252
Synonym:
Target: FXR, GPCR19, Autophagy
SB756050
T4352
Synonym: SB-756050,SB 756050
Target: GPCR19
Betazole dihydrochloride
T8599
Synonym: Betazole hydrochloride
Target: Histamine Receptor
Gut restricted-7
T11515
Synonym: GR-7
Target: Potassium Channel
Ursodeoxycholic acid sodium
T29078
Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium
Target: FXR, Endogenous Metabolite, GPCR19
Glycolithocholic acid
T31964
Synonym: Lithocholic acid glycine conjugate,Lithocholylglycine
Target: Others
Taurochenodeoxycholic Acid
T2A2481
Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine
Target: Apoptosis, TNF, Caspase, Endogenous Metabolite
TGR5 Receptor Agonist
T1824
Synonym:
Target: GPCR19
3-Oxo-5β-cholanoic acid
T13502
Synonym: Dehydrolithocholic acid
Target: ROR
Hyodeoxycholic acid
T2968
Synonym: NSC 60672,α-Hyodeoxycholic Acid,HDCA
Target: FXR, Endogenous Metabolite, GPCR19
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TargetMol