addiction — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15275	Fenobam		GluR
	Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric mo...		GluR
T22994	ML 154		Neuropeptide Y Receptor
	neuropeptide S receptor (NPSR) antagonist		Neuropeptide Y Receptor
T8959	OS-3-106		Dopamine Receptor
	OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay.		Dopamine Receptor
T4246	Varenicline dihydrochloride		AChR
	Varenicline dihydrochloride is a Selective α4β2 nicotinic acetylcholine receptor partial agonist.		AChR
T28167	NGB 2904	NGB2904 HCl,NGB-2904,NGB2904	Others , Dopamine Receptor , 5-HT Receptor
	NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag...		Others , Dopamine Receptor , 5-HT Receptor
T14767	BP 897 hydrochloride		Dopamine Receptor
	BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors ...		Dopamine Receptor
T10432L	AZD-8529 mesylate		GluR
	AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 ...		GluR
T9100	BP 897	2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-	Dopamine Receptor
	BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 ...		Dopamine Receptor
T0963	Naltrexone hydrochloride	Depade,Trexan,Naltrexone HCl,Antaxone	Opioid Receptor
	Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.		Opioid Receptor
T61562	CB1R Allosteric modulator 3		cAMP , Cannabinoid Receptor
	CB1R Allosteric modulator 3 is a potent CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP and β-Arrestin, and can be used for the study of obesity and nicotine addiction.		cAMP , Cannabinoid Receptor
TP1981L	Neuropeptide S (Mouse) acetate		Neuropeptide Y Receptor
	Neuropeptide S (Mouse) acetate is a bioactive peptide. Neuropeptide S (Mouse) acetate, as a neurotransmitter/neuromodulator of 20 amino acids, can be used for the research of arousal, anxiety, locomotion, feeding behavio...		Neuropeptide Y Receptor
T50112	5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride		Others
	5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride is a potent and selective antagonist of metabotropic glutamate receptor 5 (mGluR5). It has been shown to be effective in several neurological disorders, inclu...		Others
T0056	Oxeladin citrate		Others
	Oxeladin citrate is a highly potent and effective cough suppressant, which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is no risk of add...		Others
T50100	3-hydroxy-3-phenylpentanamide		Others
	3-hydroxy-3-phenylpentanamide is a chiral compound belonging to the class of beta-hydroxyamides. In neurology, it has been shown to have neuroprotective effects against ischemic brain injury and cerebral hemorrhage. In p...		Others
T69814	Neramexane Free Base
	Neramexane Free Base is a drug related to memantine, which acts as an NMDA antagonist and has neuroprotective effects. It is being developed for various possible applications, including treatment of tinnitus, Alzheimer's...
T83505	[DAla2] Dynorphin A (1-9) (porcine)
	[DAla2] Dynorphin A (1-9) (porcine) is a dynorphin utilized in research related to analgesic, addiction, and depression studies.
T11377	GDC-0276		Others
	GDC-0276, a potent, selective, reversible, and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM, offers potential for pain treatment while overcoming limitations associated with current pain medications, inclu...		Others
T16563	Pozanicline	ABT-089	AChR
	Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine...		AChR
T38903	(S)-UFR2709	(S)-UFR2709
	(S)-UFR2709 is a competitive antagonist of the nicotinic acetylcholine receptor (nAChR), exhibiting a greater affinity for α4β2 nAChRs compared to α7 nAChRs. It effectively reduces anxiety and ethanol consumption, as wel...
T70433	Antalarmin
	Antalarmin is a CRF-1 antagonist. By blocking CRF-1 activity the release of ACTH is reduced, and chronic stress is decreased in response to chronic stress. Antalarmin could be useful in reducing the adverse health conseq...