z3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3042	JAK2 Inhibitor V	JAK2 Inhibitor V Z3,Z3	JAK
	JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.		JAK
T77678	TZ3O		AChR
	TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type model in rats, and can be used in the study of Alzheimer's ...		AChR
T4443	AZ32		ATM/ATR
	AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.		ATM/ATR
T5172	AZ304		c-Fms , Raf , p38 MAPK , Autophagy
	AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).		c-Fms , Raf , p38 MAPK , Autophagy
T19671	AZ31	AZ 31,AZ-31	ATM/ATR
	AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK f...		ATM/ATR
T2689	AZ3146	AZ 3146	Kinesin
	AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.		Kinesin
TQ0012	AZ3451		Protease-activated Receptor
	AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).		Protease-activated Receptor
T23764	AZ3976	AZ 3976,AZ-3976	PAI-1
	AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.		PAI-1
T9658	DCZ3301	NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base)	Others
	DCZ3301 is a novel aryl-guanidino inhibitor.		Others
T5182	AMZ30		Others
	AMZ30 is a selective inhibitor of PME-1 (IC50: 600 nM). It also reduces the demethylated form of PP2A in living cells.		Others
T81725	Mz325		HDAC
	Mz325 serves as a dual inhibitor of both HDAC and Sirt2, exhibiting an IC50 of 9.7 µM against Sirt2, which are implicated in the pathogenesis of cancer and neurodegenerative diseases [1].		HDAC
T71098	AZ3971
	AZ3971 is a potent BACE1 inhibitor. AZ3971 blocks BACE1-mediated cleavage of APP and inhibits Aβ42 production HEK cells overexpressing the APP protein which carries the Swedish mutation (HEK.APPswe).
T126167	Kudinoside LZ3
	Kudinoside LZ3 is a useful organic compound for research related to life sciences. The catalog number is T126167 and the CAS number is 1239453-03-2.
T62511	AZ3391
	AZ3391 is a quinoxaline derivative that is a potent inhibitor of PARP. AZ3391 has potential for the study of diseases and conditions occurring in central nervous system tissues (e.g., brain and spinal cord).
T27522	GZ389988	GZ-389988,GZ 389988
	GZ389988 is a potent Trk inhibitor.
T71151	Z36
	Z36 is a novel Bcl-xL inhibitor, upregulating the expression levels of FAM134B, LC3, and Atg9, inducing autophagy along with autophagic cell death, resulting in ER stress and the unfolded protein response (UPR).
T69783	Z30529104
	Z30529104 is a Rpn11 inhibitor.